Abstract:Isolated plasma membranes from human thymocytes or peripheral T lymphocytes upon their reconstitution with envelope glycoproteins of Sendai virus, afforded membrane vesicles that fused efficiently with human peripheral B cells. The b cells thus obtained acquired the ability to form regular rosettes at 4 degrees C with sheep red blood cells. However, only B cells modified by fusion with thymocyte membranes formed stable rosettes at 37 degrees C, a property which distinguished thymocytes from peripheral T cells.… Show more
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