“…ND
No significant reductions in human biting rate, sporozoite rate or EIR for all interventions | No significant reductions in malaria incidence, prevalence or parasite density for ITPS + LLIN, UC of LLIN or LLIN + IRS compared to targeted LLIN | [21] | Significantly greater proportions of parous mosquitoes and indoor resting vectors in ITPS + LLIN villages |
IRS | Bendiocarb (400 mg/m 2 ) | All house walls |
kdr allele frequency increased in all intervention groups |
PermaNet ® 2.0 LLIN | Deltamethrin (55 mg/m 2 ) | Universal coverage |
Balombo, Angola, community-level | Polyethylene sheeting (ITPS) (ZeroFly®) | Deltamethrin (360 mg/m 2 ) | Full coverage | Deltamethrin LLIN (PermaNet ® 2.0; 55 mg/m 2 ) |
An. funestus
ND and other minor anopheline spp. | Significant reductions in indoor vector population density (82% for ITPS + LLINs; 78% for IRS; 73% for WL) and intensity of mosquito bites in most intervention villages, measured using anti- Anopheles saliva IgG antibodies levels | Significant reductions in malaria incidence (58% for ITPS + LLINs; 54% for IRS; 51% for WL) | [45] |
IRS (lambdacyhalothrin; 25 mg/m 2 ) |
Polyethylene WL (ZeroVector ® ) | Deltamethrin (175 mg/m 2 ) |
EIR entomological inoculation rate, Hb haemoglobin, IRS indoor residual spraying, ITPS Insecticide-treated plastic sheeting, LLIN long-lasting insecticidal net, ND not described, r resistant to one or more insecticides under investigation, s susceptible to one or more insecticides under investigation, UC universal coverage, WL wall lining
a Indicates traditional, permanent rural households or villages, unless otherwise specified
b Full coverage defined as four inner house walls, all interior surfaces in temporary structures or all interior surfaces in a λ-shaped tent, as applicable
c Outcomes reported relative to untreated control, unless otherwise specified
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