Human amnion as a bioprosthesis for bile duct reconstruction in the pig

Application of amniotic membranes in reconstructive surgery of internal organs—A systematic review and meta‐analysis

“…The PRISMA flowchart is shown in Figure 2. Sixty references containing 26 human studies (Ambrus, 1967; Barski et al., 2015; Catalano & Conticello, 1968; De Weerd et al., 2013, 2020; Eichberg et al., 2018, 2019; Frigerio et al., 2019; Ghahramani et al., 2017; Kakabadze et al., 2016; Kumar et al., 2015; Marton et al., 2021; Pignatti et al., 2020; Price & Price, 2016; Razzaghi et al., 2020; Rohleder et al., 2013; Schoellhammer et al., 2018; Schrimpf, 1954; Singh et al., 2011; Tahami et al., 2020; Tomita et al., 2012; Ts'ao, 1960; Tumanov et al., 2006; Turchan et al., 2018; Walker et al., 2018; Zmijewski & Pietraszek, 2005) and 36 animal studies (Barski et al., 2017; Brown et al., 2014; Demir et al., 2021; Ercin et al., 2019; Erdener et al., 1992; Ferhatoglu et al., 2019; Fishman et al., 1987; Francisco et al., 2016; Ghahramani et al., 2014; Güneş et al., 2016, 2017; Hariastawa et al., 2020; Iijima et al., 2007; Ismail, Marcos, et al., 2009; Ismail, Ramsis, et al., 2009; Kesting et al., 2008, 2010; Li et al., 2019; Liu et al., 2021; Mohajeri et al., 2014; Moslemi et al., 2016; Orman et al., 2020; Rohleder et al., 2013; Roshanravan et al., 2014; Schimidt et al., 2010; Scott et al., 2021; Scudamore et al., 1988; Senthil‐Kumar et al., 2016; Tomita et al.,…”

“…Price, 2016;Razzaghi et al, 2020;Rohleder et al, 2013;Schoellhammer et al, 2018;Schrimpf, 1954;Singh et al, 2011;Tahami et al, 2020;Tomita et al, 2012;Ts'ao, 1960;Tumanov et al, 2006;Turchan et al, 2018;Walker et al, 2018;Zmijewski & Pietraszek, 2005) and 36 animal studies(Barski et al, 2017;Brown et al, 2014;Demir et al, 2021;Ercin et al, 2019;Erdener et al, 1992;Ferhatoglu et al, 2019;Fishman et al, 1987; Francisco et al, 2016;Ghahramani et al, 2014;Güneş et al, 2016Güneş et al, , 2017Hariastawa et al, 2020;Iijima et al, 2007;Ismail, Marcos, et al, 2009;Ismail, Ramsis, et al, 2009;Kesting et al, 2008Kesting et al, , 2010Li et al, 2019;Liu et al, 2021;Mohajeri et al, 2014;Moslemi et al, 2016;Orman et al, 2020;Rohleder et al, 2013;Roshanravan et al, 2014;Schimidt et al, 2010;Scott et al, 2021;Scudamore et al, 1988;Senthil-Kumar et al, 2016;…”

“…months(Fishman et al, 1987;Kesting et al, 2010;Scudamore et al, 1988;Tomita et al, 2012;Tsuda et al, 1999). Multilayered AM reported more resistant to degradation(Barski et al, 2017;Kesting et al, 2008Kesting et al, , 2010.3.4.4 | Graft rejectionThree human studies reported on graft rejection and all showed no signs of rejection(Barski et al, 2015;De Weerd et al, 2020;Tomita et al, 2012).…”

Advances in the generation of bioengineered bile ducts

“…The challenges in culturing cholangiocytes until recently have led to the use of multiple acellular constructs for bile duct repair or replacement [27], [32], [62]- [69]. More specifically, collagen, small intestinal submucosa, and human amnion combined with a polyglycolic acid (PGA) mesh have been used as bio-degradable scaffolds to successfully repair CBD wall defects [33], [65], [67], [68]. In all cases the scaffolds were completely absorbed and replaced by a healthy, epithelized and vascularized wall indistinguishable from the native CBD [33], [65], [67], [68].…”

“…More specifically, collagen, small intestinal submucosa, and human amnion combined with a polyglycolic acid (PGA) mesh have been used as bio-degradable scaffolds to successfully repair CBD wall defects [33], [65], [67], [68]. In all cases the scaffolds were completely absorbed and replaced by a healthy, epithelized and vascularized wall indistinguishable from the native CBD [33], [65], [67], [68]. These studies paved the way and provided invaluable information for the generation of tubular constructs; however the clinical applications of CBD patches remain somewhat limited mainly to the repair of iatrogenic CBD wall defects.…”