Abstract:Background. Polymorphisms in genes, which is involved in the renin-angiotensin system, play an important role in the pathogenesis of coronary heart disease (CHd). Polymorphism of c.803t>C in the human angiotensinogen gene results in methionine (M) to threonine (T) substitution at codon 268 (p.Met268Thr), which traditionally has been known as M235T. This polymorphism may contribute to cardiovascular diseases. Objectives. The aim of this study was to investigate the association between p.Met268Thr polymorphism i… Show more
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