Human Aeromonas Infections

Davis, William; Kane, James G.; Garagusi, Vincent F.

doi:10.1097/00005792-197805000-00006

Cited by 239 publications

(21 citation statements)

References 0 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…Aeromonas salrnonicida and Aerornonas hydrophila are both important pathogens of fish (13,14) and A . hydrophila is known to cause a variety of clinical infections in man and other animals (15,16). Because outer membrane fragments can be isolated directly from cell-free culture medium by ultracentrifugation they provide a rapid means of access to outer membrane material which may be useful in structural studies and in a detailed examination of the role of outer membrane components in pathogenesis.…”

Section: Introductionmentioning

confidence: 99%

Identification and characterization of outer membrane fragments released by Aeromonas sp.

MacIntyre¹,

Trust²,

Buckley³

1980

Can. J. Biochem.

View full text Add to dashboard Cite

Aeromonas hydrophila and Aeromonas salmonicida were shown to release "blebs" or fragments averaging 20-30 nm in diameter. The protein composition of the fragments was very similar to that of the corresponding outer membrane by sodium dodecyl sulphate--polyacrylamide gel electrophoresis and the fragments were shown to contain phospholipid and lipopolysaccharide. The results therefore indicate that the blebs are derived from the outer membrane of these organisms. Fragments isolated directly by differential ultracentrifugation were indistinguishable from fragments isolated by salt fractionation and gel filtration in chemical composition, protein composition, and density. However fragments isolated directly contained much less glycerophospholipid-cholesterol acyltransferase than those isolated by salt fractionation. The potential usefulness of membrane fragments to the bacteria and as a tool in the study of outer membrane structure and function is discussed.

show abstract

Section: Introductionmentioning

confidence: 99%

Identification and characterization of outer membrane fragments released by Aeromonas sp.

MacIntyre¹,

Trust²,

Buckley³

1980

Can. J. Biochem.

View full text Add to dashboard Cite

show abstract

“…They have long been known to cause disease in coldblooded animals but in recent years increasing attention has been given to their role as human pathogens. Major series and reviews (2-6) indicate that they may cause a wide spectrum of disease including septicaemia, especially in the immunocompromised patient, soft tissue infections (sometimes with myonecrosis), diarrhoea, and miscellaneous diseases such as endocarditis (3), meningitis (3), septic arthritis and osteomyelitis (3,7,8), hepatic abscess (9), nosocomial pneumonia (10) and urinary tract infection (10).Three of the five Aeromonas spp. recognized, Aeromonas hydrophila, A eromonas caviae and A eromonas sobria, are motile, and two, Aeromonas salmonicida and Aeromonas media, non-motile.…”

mentioning

confidence: 99%

Wound infection with aerogenicAeromonas strains: A review of twenty-seven cases

Isaacs

Paviour

Bunker

et al. 1988

Eur. J. Clin. Microbiol. Infect. Dis.

View full text Add to dashboard Cite

Aeromonas spp. have been implicated in a wide spectrum of human disease including wound infection. A review is made of local experience of 27 wound infections from which aerogenic strains of Aeromonas were recovered; of these, Aeromonas was isolated in pure culture from five infections. Twenty-five infections were related to trauma and were community acquired, while two were probably nosocomial. Of the 25 community acquired infections, 16 were associated with contamination by soil and one with water. Twenty-six cases were surgically debrided or a limb or digit amputated, but in only one case was amputation performed because of uncontrolled infection. Fifteen patients received antibiotics inappropriate for the infection, yet the outcome was uniformly good. This series is discussed with a review of the English language literature. Aeromonas is most likely to be isolated when there is contamination of a wound by soil or water; adequate surgical debridement is probably of primary importance.

show abstract

“…They are also identified as a significant bacterial pathogen of fish and other cold-blooded animals (Bullock 1961;Shotts et al 1972) and man (Davis et al 1978). Variation in virulence in fish was observed among various isolates of A. hydrophila (De Figueiredo and Plumb 1977;Lallier et al 1980).…”

mentioning

confidence: 99%

Aeromonas hydrophila in rainbow trout: relation between virulence and surface characteristics

Mittal¹,

Lalonde²,

LeBlanc³

et al. 1980

Can. J. Microbiol.

109

View full text Add to dashboard Cite

Motile Aeromonas isolated from fish were studied for their virulence in fish in relation to some surface characteristics. The results showed that only the most virulent strains of A. hydrophila used in this study shared a common O antigen, did not agglutinate in acriflavine, settled down after boiling, and were resistant to the bactericidal action of fresh normal mammalian serum. The least virulent strains could not be grouped into this O antigenic group, they did not settle after boiling, and were sensitive to the bactericidal effect of serum. It is suggested that agglutination in acriflavine, stability after boiling, and sensitivity to normal fresh serum could be used for screening the Aeromonas isolates for virulence in fish.

show abstract

Human Aeromonas Infections

Cited by 239 publications

References 0 publications

Identification and characterization of outer membrane fragments released by Aeromonas sp.

Identification and characterization of outer membrane fragments released by Aeromonas sp.

Wound infection with aerogenicAeromonas strains: A review of twenty-seven cases

Aeromonas hydrophila in rainbow trout: relation between virulence and surface characteristics

Contact Info

Product

Resources

About