Human absorption of fish oil fatty acids as triacylglycerols, free acids, or ethyl esters

The metabolism and availability of essential fatty acids in animal and human tissues

“…The processes of lipid digestion and absorption have been reviewed several times in the last few years (B6zard and Bugaut, 1986;Bernard and Carlier, 1989;Thomson et al, 1989;Carlier ef al, 1991 (Lawson and Hughes, 1988b). However, hydrolysis takes place, probably less rapidly but completely.…”

Short-term Effects of Different Fish Oil Formulations on Tissue Absorption of Docosahexaenoic Acid in Mice Fed High- and Low-Fat Diets

“…Larry D 9 showed that DHA and EPA were readily absorbed ≥ 95 as free acids, but less readily as TG and EE. The different forms may affect the absorption and metabolism of DHA in vivo.…”

Digestion and absorption of polyunsaturated fatty acids

“…Vahouny (1985) and Chen et al (1987a) demonstrated in rats that the total fatty acids recovered in lymph after respective salmon oil or menhaden oil and fish oil concentrate feeding were significantly lower than levels found after corn oil feeding. Lawson and Hughes (1988a) (Johnston, 1976 (Shiau et al, 1985;Shiau, 1990 (Stremmel, 1988 (Bass, 1985 (Clark and Hubscher, 1960), rather than the glycerol-3-phosphate pathway (Kern and Borgstr6m, 1965 (Lawson and Hughes, 1988a,b (Cardell et al, 1967;Carlier, 1971;Sabesin, 1976;Bernard et al, 1979b (Vallot et al, 1985). In contrast, in the same experimental conditions, only 1.8-2.2% of infused 14 C linoleic acid and 2.6 to 3% of infused 14 C arachidonic acid were recovered in the mesenteric portal venous blood mained lower than 5% of the infused radioactivity (fig 5).…”