Huge Focal Nodular Hyperplasia Presenting in a 6-Year-Old Child: A Case Presentation

Abstract

Focal nodular hyperplasia (FNH), a benign lesion of the liver, is characterized by hepatocyte hyperplasia and a central stellate scar. FNH is relatively prevalent in healthy adults, but it is uncommon for FNH to be diagnosed in children. Herein, we report the case of a 6-year-old child (male) with a huge FNH. The child presented to the clinic with a two-year history of a hepatic space-occupying lesion. The physical examination and liver function testing were near-normal. The abdominal ultrasound scan showed a 6.1*5.2 cm lesion with an inhomogeneous and welldemarcated low echo in the right lobe of the liver. On computed tomography (CT) imaging, a plain scan displayed a 7.1*6.4 cm circular shadow with a slightly low density and a central star-like scar in the right hepatic lobe. The tumor showed clear enhancement in the arterial phase and slightly decreased enhancement in the venous phase. As a result of uncertainty in the imaging and needle biopsy results, this child underwent surgical resection of the tumor. After surgery, we found that the tumor was shown to be enlarged in the right posterior liver, well-defined, yellow-totan in color, and 11*8*7 cm in size, which is larger than previously reported. The histopathologic evaluation of the surgical specimen was consistent with focal nodular hyperplasia (FNH).