Huge fetal hepatic Hemangioma: prenatal diagnosis on ultrasound and prognosis

Li, Jiaoling; Geng, Xianguo; Chen, Kunshan; He, Qiuming; Xiao-fen, Li; Yang, Boyang; Qian, Fang

doi:10.1186/s12884-017-1635-7

Cited by 19 publications

(21 citation statements)

References 23 publications

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“…16 The risk of neonatal death due to complications of preterm birth is at least 12 times higher for an African baby than for a European baby. 15 …”

Section: Resultsmentioning

confidence: 99%

See 1 more Smart Citation

<p>Neonatal Survival in Sub-Sahara: A Review of Kenya and South Africa</p>

Masaba¹,

Mmusi-Phetoe²

2020

JMDH

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Introduction The majority (99%) of the children who die during the first 4 weeks of life do so in the poorer parts of the world, especially in sub-Saharan Africa and South Asia. In 2018, sub-Saharan Africa had a neonatal mortality rate of 28 deaths per 1000 live births. The purpose of the review was to explore and describe the trends of neonatal mortality within the two sub-Saharan countries. Methods We did a literature search in biomedical databases of data published, in English, between Jan 1, 1975, and November 30, 2019. The databases included Scopus, Web of Science, Science Direct, Cochrane Library, PUBMED, OVID and Google scholar. The keywords used in the search: “Neonatal Survival”, “Sub-Sahara”, “Kenya” and “South Africa”. Results The search generated 2209 articles of which only 27 met the inclusion criteria. The present study qualitatively analysed data. Data were presented and organized under two thematic domains: 1) trends of national neonatal mortality rates in South Africa and Kenya and 2) causes of neonatal mortality. Conclusion The current review results noted that in 2018, the neonatal mortality rate for Kenya was 19.6 deaths per 1000 live births. The neonatal mortality rate has fallen gradually from 35.4 deaths per 1000 live births in 1975. On the other hand, South Africa has had its neonatal mortality rate fall from 27.9 deaths per 1000 live births in 1975 to 10.7 deaths per 1000 live births in 2018. Most neonatal deaths resulted in preterm birth complications followed by intrapartum-related events for the two countries. Within the sub-Saharan region, disparities exist as neonates born in South Africa are more likely to survive during the neonatal period compared to Kenya.

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“…16 The risk of neonatal death due to complications of preterm birth is at least 12 times higher for an African baby than for a European baby. 15 …”

Section: Resultsmentioning

confidence: 99%

“…22 Prematurity is a major cause of neonatal mortality and morbidity as well as a significant contributor to long-term adverse health outcomes. 15 , 27…”

Section: Resultsmentioning

confidence: 99%

<p>Neonatal Survival in Sub-Sahara: A Review of Kenya and South Africa</p>

Masaba¹,

Mmusi-Phetoe²

2020

JMDH

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“…The other reason is that IHH contains arteriovenous malformations and venous, lymphatic or capillary components thus cystic cavity inside is regularly seen and this important feature was ignored by the sonographer. [ 3 , 8 , 15 , 16 ] In addition, the lesion seemed to have an ill-defined margin, irregular shape and partial capsula and these appearances were consistent with HBL. [ 17 , 18 ]…”

Section: Discussionmentioning

confidence: 99%

“…[ 7 ] However, the overlap of imaging features between IHH and HBL may confuse the differential diagnosis in utero, and there is very few research about the prenatal differential diagnosis. [ 8 ] The final diagnosis depends on the postnatal ultrasound, contrast-enhanced computerized tomography and the biopsy of the hepatic lesions. [ 9 ]…”

Section: Introductionmentioning

confidence: 99%

Infantile hepatic hemangioma misdiagnosed by prenatal ultrasonography

2021

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Rationale: The drastic differences in treatment and prognosis of infantile hepatic hemangioma (IHH) and hepatoblastoma (HBL) make accurate prenatal diagnosis imperative. The retrospective comparisons of ultrasonic features between fetal IHH and HBL have been reported before, but clinically, the differential diagnosis in utero is very difficult and can lead to prenatal misdiagnosis. Patient concerns: A 27-year-old woman at 30 gestational weeks underwent the routine prenatal examination. A heterogeneous solid mass of the fetus, with close relationship to the liver, was recognized by ultrasound. Diagnosis: A diagnosis of HBL was highly considered. Interventions: The fetus was aborted and the autopsy was performed. Outcomes: The histological outcome was IHH. Lessons: The prognosis of fetal IHH and HBL is very different, so an accurate diagnosis prenatally is crucial and indispensable. The radiologist and clinician should differentiate between IHH and HBL, especially since the fetus can have serious complications.

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“…Fetal hepatic hemangiomas are rarely reported; hence, their exact incidence rate remains undetermined. 3 Congenital hepatic hemangiomas, may reach maximum size at birth and, in some cases, gradually disappear. Small hepatic hemangiomas are often asymptomatic and seldom require treatment whereas, huge hepatic hemangiomas (Diameter >4 cm) are less frequently reported and can cause serious complications.…”

Section: Introductionmentioning

confidence: 99%

Fetal hepatic hemangioma: a case report

Shresth¹,

Bajracharya²,

Parajuli³

et al. 2019

J Chitwan Med Coll

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Fetal liver tumors represent approximately 5% of all congenital tumors and hemangiomas account for approximately 15% of all fetal liver tumors. Hemangioma and hemangioendothelioma are benign vascular tumors but they are associated with a significant morbidity and mortality due to high output congestive heart failure and arteriovenous shunting. Ultrasound features of hepatic hemangioma can overlap with arteriovenous malformation. This is a case report of fetal hepatic hemangioma with aretriovenous shunting detected on routine anomaly scan at 20 weeks of gestation in 22 years old Nepalese women who was asymptomatic. Prenatally, a 3.2cm x 2.8cm multicystic mass was seen in the left hypochondrium of the fetal abdomen displacing the stomach. On color Doppler examination, the mass showed internal color flow and multiple tortuous dilated vessels noted around the lesion. After counseling regarding the lesion to the mother and her family; decision to abort the fetus was made. Autopsy was done for the final diagnosis of the lesion, which showed vascular mass in the left lobe of liver insinuating between stomach and spleen.

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Huge fetal hepatic Hemangioma: prenatal diagnosis on ultrasound and prognosis

Cited by 19 publications

References 23 publications

<p>Neonatal Survival in Sub-Sahara: A Review of Kenya and South Africa</p>

<p>Neonatal Survival in Sub-Sahara: A Review of Kenya and South Africa</p>

Infantile hepatic hemangioma misdiagnosed by prenatal ultrasonography

Fetal hepatic hemangioma: a case report

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