Hubungan kadar troponin I dan high-sensitivity troponin I dengan angiografi koroner pada pasien suspek coronary artery disease: studi di Rumah Sakit Umum Pusat dr.Wahidin Sudirohusodo Makassar-Indonesia tahun 2017

Abstract

Background: Coronary artery disease (CAD) is a narrowing of blood vessels due to the formation of atherosclerotic plaques which can cause disruption of oxygen supply to the heart. High sensitivity troponin I (hs-TnI) is a diagnostic tool for detecting heart disorders with minimal injury to the heart muscle. Aim: The study aimed to compare and observe the relationship of troponin I (TnI) and hsTnI with /RSUP dr.Wahidin Sudirohusodo Makassar. Methods: The design of the study was cross-sectional study, using primary data of blood samples from 31 suspected CAD patients who underwent coronary angiography examination at RSUP Dr.Wahidin Sudirohusodo Makassar. Samples were taken from a population of subjects who met the inclusion criteria by using consecutive sampling technique in the period of September 2018. Statistical analysis were done using descriptive statistical calculations, frequency distribution and, Spearman's correlation test. The test results were considered significant if p<0.05. Results: CAD was more common in men at the age of 50-69 years. Data analysis showed a significant correlation between TnI, hsTnI, and the degree of stenosis (p<0.001). The correlation coefficient of TnI and degree of stenosis was 0.707, hsTnI with degree of stenosis was 0.877, and TnI with hsTnI was 0.804. Conclusion: Higher levels of TnI and hsTnI are related to the severity of stenosis in CAD.

Correlation of Neutrophyl-Lymphocyte Ratio, Vessel Score based on Sullivan Scoring System, and Troponin in Acute Coronary Syndrome Patients

“…These patients tend to have a higher-than-normal spasm. [21] The findings in this study and the research conducted by Apriliani (2019) which showed a correlation between high sensitive troponin and severity of stenosis in coronary artery disease (CAD) [19,21] . The difference in the results of this study can be caused because the two studies used hs-Troponin I, which has very high sensitivity compared to troponin I [19] .…”

“…[21] The findings in this study and the research conducted by Apriliani (2019) which showed a correlation between high sensitive troponin and severity of stenosis in coronary artery disease (CAD) [19,21] . The difference in the results of this study can be caused because the two studies used hs-Troponin I, which has very high sensitivity compared to troponin I [19] . In addition, research by Laufer et al (2010) showed that troponin levels in the blood could be elevated even in patients with mild CAD, and this troponin increase is not always accompanied by myocardial infarction.…”

“…In addition, estrogen also has antioxidant, vasoprotective, and antithrombotic effects. [18,19] The dominating age category was patients aged 51- ). [17] Based on the ACS category and type of coronary artery lesion, this study was dominated by STEMI patients with simple lesions (42 patients [48.28%]), followed by STEMI patients with multiple lesions (31 patients [35.63%]), then followed by UAP patients with simple lesions and multiple lesions respectively were two patients (2.30%) and three patients (3.45%), and NSTEMI patients with simple lesions and multiple lesions were respectively three patients (3.45%) and six patients (6.90%).…”