Hslc_fuge: High Speed and Low Cost Laboratory Centrifuge for Genomic Dna Purification

Abstract

A laboratory centrifuge is a piece of laboratory equipment, driven by a motor, which spins liquid samples at high speed. There are various types of centrifuges, depending on the size and the sample capacity. Like all other centrifuges, laboratory centrifuges work by the sedimentation principle, where the centripetal acceleration is used to separate substances of greater and lesser density. The information for synthesizing the molecules that allow organisms to survive and replicate is encoded in genomic DNA. Extracted and puri¯ed genomic DNA is very important for the analysis of single nucleotide polymorphisms (SNPs), disease states, and for many other multiplex and real-time PCR applications. The aim of this work is to design a genomic DNA extraction system that satis¯es downstream application needs necessary for the successful completion of experiments and able to isolate a puri¯ed genomic DNA from many sources from bacteria to humans and also is able to encompass tissues from blood to muscle and from leaf to seed. Results revealed that the proposed system works with high e±ciency and spins at up to 12,000 RPM to facilitate separation of the di®erent phases of the extraction.

A diagnostic genomic signal processing (GSP)-based system for automatic feature analysis and detection of COVID-19

“…This system can assist in the rapid diagnosis of COVID-19 with highly acceptable accuracy results as it does not depend on the previously mentioned classical diagnostic methods’ disadvantages. It is executed simply by separating DNA sequences using the DNA centrifuge [ 57 ] and continuing with program steps that take just a few minutes. All the results are acceptable and satisfying, but the KNN results are perfect for the created classification system getting the best and most efficient diagnosis method.…”