HPV genotypic spectrum in Jilin province, China, where non-vaccine-covered HPV53 and 51 are prevalent, exhibits a bimodal age-specific pattern

Hao, Shuai; Wang, Chunyan; Liu, Siwen; He, Jiaxue; Jiang, Yanfang

doi:10.1371/journal.pone.0230640

Cited by 29 publications

(27 citation statements)

References 38 publications

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“…And in spite of low percentage of positive hr HPV in our samples, our study revealed that there was increase in p ercent ag e o f posit ive h rHPV wit h in crease sev erity o f cyto log ical ab no rmalit y. And this approved by many other study like Turkish study (24) and Chinese study (25) .…”

Section: Discussionsupporting

confidence: 53%

Cervical cytological abnormalities among attendants to cancer early detection clinic in Baghdad, Iraq

Sura¹,

Al-Niyazee²,

Ibraheem³

et al. 2021

ASRO

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Introduction: Cervical cancer is the easiest gynecologic cancer to be prevented and diagnosed using regular screening tests and follow-up and the conventional cytology test can detect pre-cancerous and cancerous cells in uterine cervix. The main objective of the study is to analysis various spectrum of cytopathological abnormalities of both symptomatic and asympto matic wo men and also to determine the possible association of this abnormality with risk factors and to address the need for cancer screening programs in Iraq. Methods: A retrospective study of all cervical s mears received and processed at the Department of Pathology, AL-Alwiya Teaching Hospital, between January 2018 and December 2019.Those with inadequate data were excluded from the study. Classification was by the Bethesda system and analysis was by simple statistical methods. Results: A total of 1096 wo men were enrolled in this study, 71.9% of wo men had normal cytology, and 28.1% of wo men had abnormal cytology, the prevalence of abnormal cytology not association with any studied risk factors (age, age at marriage, HPV in fection, parity, duration of hormonal contraception use, smoking habit) . Conclusion: Screening for cervical cancer would assist in early diagnosis and treatment of such cancer who are not exposed to risk factors.

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Section: Discussionsupporting

confidence: 53%

Cervical cytological abnormalities among attendants to cancer early detection clinic in Baghdad, Iraq

Sura¹,

Al-Niyazee²,

Ibraheem³

et al. 2021

ASRO

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“…The overall HPV-positive detection rate in normal women ranges from 7.2% (Malaysia) to 41.7% (Hong Kong). The HPV genotypes commonly detected in these regions are HPV16, 18, 52, 58, 31, 33, 35, 39, 45, 51, 56, 59, 68, 6, 11, 42, 43, and 81 [ 17 , 18 , 19 , 20 , 21 , 22 , 23 , 24 , 25 , 26 , 27 , 28 , 29 , 30 , 31 , 32 , 33 , 34 , 35 , 36 , 37 , 38 , 39 , 40 , 41 , 42 , 43 , 44 , 45 , 46 , 47 , 48 , 49 , 50 , 51 , 52 , 53 , 54 , 55 , 56 , 57 , 58 , 59 , 60 ].…”

Section: Hpv Genotype Distribution In East Southeast and South Asiamentioning

confidence: 99%

Section: Hpv Genotype Distribution In East Southeast and South Asiamentioning

confidence: 99%

“…As China is a geographically wide country, we collated studies on the distribution of HPV genotypes according to traditional geographical regions: East, South, Southwest, Northwest, Central, North, and Northeast China. In general, the most prevalent hrHPV genotypes detected in normal uterine cervixes were found to be HPV16, 52, and 58, followed by HPV18, 31,33,35,39,45,51,56,59, and 68 [17][18][19][20][21][22][23][24][25][26][27][28][29][30][31][32][33][34][35][36][38][39][40][41][42][43][44][45]63]. The most commonly detected low-risk Human Papillomavirus (lrHPV) types were found to be HPV6, 11, and 81.…”

Section: Hpv Genotype Distribution In East Southeast and South Asiamentioning

confidence: 99%

“…The most commonly detected low-risk Human Papillomavirus (lrHPV) types were found to be HPV6, 11, and 81. Based on age groups, HPV detection rate was shown to be the highest among women of age >55, followed by 30-55 years old, and <30 years old [17][18][19][20][21][22][23][24][25][26][27][28][29][30][31][32][33][34][35][36][38][39][40][41][42][43][44][45]63].…”

Section: Hpv Genotype Distribution In East Southeast and South Asiamentioning

confidence: 99%

See 2 more Smart Citations

Current Updates on Cancer-Causing Types of Human Papillomaviruses (HPVs) in East, Southeast, and South Asia

Xia

Long

et al. 2021

Cancers

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Human papillomavirus (HPV) infection remains one of the most prominent cancer-causing DNA viruses, contributing to approximately 5% of human cancers. While association between HPV and cervical cancers has been well-established, evidence on the attribution of head and neck cancers (HNC) to HPV have been increasing in recent years. Among the cancer-causing HPV genotypes, HPV16 and 18 remain the major contributors to cancers across the globe. Nonetheless, the distribution of HPV genotypes in ethnically, geographically, and socio-economically diverse East, Southeast, and South Asia may differ from other parts of the world. In this review, we garner and provide updated insight into various aspects of HPV reported in recent years (2015–2021) in these regions. We included: (i) the HPV genotypes detected in normal cancers of the uterine cervix and head and neck, as well as the distribution of the HPV genotypes by geography and age groups; (ii) the laboratory diagnostic methods and treatment regimens used within these regions; and (iii) the oncogenic properties of HPV prototypes and their variants contributing to carcinogenesis. More importantly, we also unveil the similarities and discrepancies between these aspects, the areas lacking study, and the challenges faced in HPV studies.

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Prevalence and genotype distribution of high‐risk HPV infection among women in Beijing, China

Zhu

Wang

et al. 2021

Journal of Medical Virology

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Cervical cancer (CC) is highly associated with high‐risk human papillomavirus (HPV) infection and genotype distribution of high‐risk HPV (HR‐HPV) infection varies greatly in different regions. Clinical specimens were collected from 46 365 patients at Beijing Friendship Hospital, Capital Medical University from January 2017 to December 2020. HPV DNA genotype testing was performed using real‐time PCR. The infection rates based on disease group were compared using the χ 2 test. The linear‐by‐linear association test and gamma value were used to assess the changes in HPV prevalence over calendar year and age group. A total of 10 514 women were infected with HR‐HPV, with an overall positive rate of 22.7%. The most prevalent HR‐HPV types were HPV52, 58, 16, 51, and 66, and HPV59 had a higher prevalence except for HPV16, 58, and 52 in the CC group. Single infection of HR‐HPV was dominant among different disease groups. The infection rate of HR‐HPV decreased first and then increased from below 20 years old to over 60 years old. There were significant differences in the HR‐HPV infection rates among the age and disease groups. Our findings demonstrate that the genotype distribution of HR‐HPV varied with age and diseases. The HR‐HPV genotypes prevalence was found to be directly useful for local governments to promote HPV targeted vaccination in the study region.

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HPV genotypic spectrum in Jilin province, China, where non-vaccine-covered HPV53 and 51 are prevalent, exhibits a bimodal age-specific pattern

Cited by 29 publications

References 38 publications

Cervical cytological abnormalities among attendants to cancer early detection clinic in Baghdad, Iraq

Cervical cytological abnormalities among attendants to cancer early detection clinic in Baghdad, Iraq

Current Updates on Cancer-Causing Types of Human Papillomaviruses (HPVs) in East, Southeast, and South Asia

Prevalence and genotype distribution of high‐risk HPV infection among women in Beijing, China

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