HPV associated oral lesions among HIV/AIDS patients - a cross sectional study

Abstract

BackgroundOral HPV infection results from increase in oral based immune suppression in the HIV co infected individual that cannot be restored and is possibly compromised further by HAART. Unfortunately, little is known about the prevalence and immune response against oral HPV infection.The aim of the present study was to study the prevalence of HPV associated lesions in a group of patients with HIV who were on HAART. MethodsCross sectional, descriptive and observational study was carried out among HIV/AIDS patients attending the ART centre, KIMS, Bangalore from January 2010 to June 2012. Previous informed consent was taken and after which a detailed oral exam, was carried out in patients considering WHO diagnostic criteria. Demographic and clinical profile of HPV associated oral lesions was recorded according to the WHO diagnostic criteria.

Baseline burden and antimicrobial susceptibility of pathogenic bacteria recovered from oral lesions of patients with HIV/AIDS in South‐Western Uganda

“…The oral microbial population predominated by pathogenic bacteria may relatively be stable in health, but any adverse changes by surgery and underlying defects in the innate or specific immune systems predispose the mouth to infections The prevalence of oral microbial (including pathogenic bacteria) lesions among patients with human immunodeficiency virus and acquired immunodeficiency syndrome (HIV/AIDS) shows a regional and geographical variation. The global report of oral microbial (including pathogenic bacteria) disease prevalence in HIV/AIDS disease was 40-50% [9], and other reports from different regions of the world include 13-45% from India [10], 43-79% from Nigeria [11], .9% from USA [12], and an average of 73% from Uganda [12]. The condition was slightly similar (5.5-57%) in a Brazilian report on patients with non-HIV having other infectious diseases [13].…”