HPTLC screening of saccharin in beverages by densitometry quantification and SERS confirmation

Chen, Qifei; Hou, Huaming; Zheng, Dan; Xu, Xueming; Xi, Xingjun; Chen, Yisheng

doi:10.1039/d1ra09416e

RSC Adv.

2022

DOI: 10.1039/d1ra09416e

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HPTLC screening of saccharin in beverages by densitometry quantification and SERS confirmation

Qifei Chen

Huaming Hou

Dan Zheng

et al.

Abstract: As a widely used artificially synthesized sweetener, saccharin faced numerous disputes associated with food safety.

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Cited by 2 publications

References 31 publications

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Simultaneous analysis of natural and artificial sweeteners in sugar-free drinks and urine samples by column-switching UHPLC-charged aerosol detection method

Cheng,

Wang,

Zheng

et al. 2024

Journal of Chromatography A

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Simultaneous analysis of natural and artificial sweeteners in sugar-free drinks and urine samples by column-switching UHPLC-charged aerosol detection method

Cheng,

Wang,

Zheng

et al. 2024

Journal of Chromatography A

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HPTLC Method Development of Herbal drugs and its Validation: An Overview

Vyas,

Jain,

Sahu

et al. 2023

RJPT

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High Performance Thin Layer Chromatography (HPTLC) is the most potent and sophisticated type of Thin Layer Chromatography (TLC). It uses chromatographic layers with the highest levels of separation, efficiency and employs high-tech equipment for every step of the process, including accurate sample application, standardised reproducible chromatogram development, and software-controlled evaluation. HPTLC is a concept that incorporates both the use of established methodologies for qualitative and quantitative analysis and a widely standardised methodology founded on scientific facts. The resolution can be increased and more exact quantitative measurements, which satisfies all quality standards for today's analytical needs. Development of an analytical technique based on HPTLC and parameter validation in line with practical assessment. It complies with standards while reducing mistakes and inquiries. Quality Control and Quality Assurance of raw materials of Plant Origin can easily and effectively be done qualitative characterization and quantitative determination of mixtures of substances, Chemical Fingerprinting by High Performance Liquid Chromatography. This review article provides fundamental principles, guidance for proper validation practise, aids in selecting the best mobile phase, and clarifies the processes of the analytical process., protocol, separation, resolution, validation process, current advancements, changes made to TLC that led to HPTLC, optimization, process control, automation, and hyphenation.

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HPTLC screening of saccharin in beverages by densitometry quantification and SERS confirmation

Abstract: As a widely used artificially synthesized sweetener, saccharin faced numerous disputes associated with food safety.

Cited by 2 publications

References 31 publications

Simultaneous analysis of natural and artificial sweeteners in sugar-free drinks and urine samples by column-switching UHPLC-charged aerosol detection method

Simultaneous analysis of natural and artificial sweeteners in sugar-free drinks and urine samples by column-switching UHPLC-charged aerosol detection method

HPTLC Method Development of Herbal drugs and its Validation: An Overview

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