HPLC-Q-Orbitrap-MS/MS phenolic profiles and biological activities of extracts from roxburgh rose (Rosa roxburghii Tratt.) leaves

Wang, Ruimin; He, Ruiping; Li, Zhaohui; Lin, Xue; Wang, Lu

doi:10.1016/j.arabjc.2021.103257

Cited by 19 publications

(9 citation statements)

References 34 publications

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“…Peak 26 (m/z 505.0993) was tentatively characterized as quercetin 3- O -6″-acetylglucoside because of its fragment ions at m/z 301.0348, corresponding to the quercetin moiety ( 26 ). Peak 29 and peak 32 were identified as kaemperol-3- O -glucuronide and kaempferol-pentoside, respectively, at their [M-H] – ion and the fragment ions at m/z 285.0389 ( 27 ). Among the abundant individual phenolics, protocatechuic acid, neochlorogenic acid, brevifolin carboxylic acid, catechin, benzoic acid, ellagic acid, hyperoside, ferulic acid, isoferulic acid, astragaline, quercitrin, quercetin, naringenin, and kaempferol derivative were detected in the free and bound phenolic extracts.…”

Section: Resultsmentioning

confidence: 99%

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Free and Bound Phenolic Profiles of Rosa roxburghii Tratt Leaves and Their Antioxidant and Inhibitory Effects on α-Glucosidase

Yang

Xian

et al. 2022

Front. Nutr.

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Rosa roxburghii Tratt (R. roxburghii) tea is a traditional Chinese beverage. This study aims to investigate and compare the phenolics in free and bound forms of two cultivars of R. roxburghii leaves, and their bioactivities. The total phenolic content of free and bound fractions was 72.71 and 17.75 mg GAE/g DW in Gui Nong No. 5 (GNN5) and 94.28 and 11.19 mg GAE/g DW in Seedless Cili (SC). A total of 37 phenolic compounds were characterized and quantified by UPLC-Q-Exactive Orbitrap/MS with ellagic acid, quercitrin, isoquercitrin, and quininic acid in free fraction, while gallic acid, ellagic acid, and hyperoside were main compounds in bound fraction. The free fraction with higher phenolic contents also showed excellent performances on antioxidant activities and α-glucosidase inhibitory potency than bound phenolics. Therefore, the results highlight that R. roxburghii leaves are a promising source enriched in phenolic constituents for functional beverages and nutritional foods.

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Section: Resultsmentioning

confidence: 99%

“…− ion and the fragment ions at m/z 285.0389(27). Among the abundant individual phenolics, protocatechuic acid, neochlorogenic acid, brevifolin carboxylic acid, catechin, benzoic acid, ellagic acid, hyperoside, ferulic acid, isoferulic acid, astragaline, quercitrin, quercetin, naringenin, and kaempferol derivative were detected in the free and bound…”

mentioning

confidence: 99%

Free and Bound Phenolic Profiles of Rosa roxburghii Tratt Leaves and Their Antioxidant and Inhibitory Effects on α-Glucosidase

Yang

Xian

et al. 2022

Front. Nutr.

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“…Supplement Fig. S2 showed the m/z information of nine selected phenolic compounds, which were identified as chicoric acid, esculetin, caffeic acid, gallic acid monohydrate, eupatilin, caffeic acid-3-glucoside, corchorifatty acid F, luteolin [ 14 , 35 , 36 ]. As shown in Table 1 and Fig.…”

Section: Resultsmentioning

confidence: 99%

PARAFAC modeling of dandelion phenolic compound fluorescence relation to antioxidant properties

Ben

Zou

et al. 2022

Food Measure

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The phenolic compounds in dandelion were extracted using different ethanol percentage solutions, identified with HPLC-MS, and their scavenging capabilities of DPPH, ABTS and OH radicals were determined. Then the excitation-emission matrix fluorescence spectroscopy coupled with parallel factor analysis (PARAFAC) was conveyed to analyze the relationship between phenolics, components scores of PARAFAC model and antioxidant capacities, based on linear regression method. The results showed that the relative content of chicoric acid, esculetin, caffeic acid, gallic acid monohydrate, eupatilin, caffeic acid-3-glucoside, corchorifatty acid F, and luteolin was higher than 0.5%, and the extraction solutions with 100% and 75% water had a better scavenging capacity of DPPH, ABTS and OH radicals. Two components PARAFAC model was identified with the comparatively higher sum of squares, core consistency values, and lower interactions numbers, and the established equations indicated the component scores had a linear regression relationship with antioxidant capacities of DPPH, and ABTS. The paper was proposed for the first time that the component scores of PARAFAC model might be treated as a useful indication for antioxidant capacity evaluation. Supplementary Information The online version contains supplementary material available at 10.1007/s11694-022-01389-z.

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“…leaf extracts. Approximately, 30 polyphenols were detected, which mainly includes gallic acid, myricetin, (+)-catechin, quercetin-3-O-galactoside, arbutin, and 3-hydroxybenzoic acid [ 73 ]. HPLC analysis of Pinus roxburghii barks and needles was carried out and quercetin was identified as the most abundant flavonol [ 11 ].…”

Section: Resultsmentioning

confidence: 99%

HPLC-DAD Based Polyphenolic Profiling and Evaluation of Pharmacological Attributes of Putranjiva roxburghii Wall.

et al. 2021

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The current study was intended to explore the phytochemical profiling and therapeutic activities of Putranjiva roxburghii Wall. Crude extracts of different plant parts were subjected to the determination of antioxidant, antimicrobial, antidiabetic, cytotoxic, and protein kinase inhibitory potential by using solvents of varying polarity ranges. Maximum phenolic content was notified in distilled water extracts of the stem (DW-S) and leaf (DW-L) while the highest flavonoid content was obtained in ethyl acetate leaf (EA-L) extract. HPLC-DAD analysis confirmed the presence of various polyphenols, quantified in the range of 0.02 ± 0.36 to 2.05 ± 0.18 μg/mg extract. Maximum DPPH scavenging activity was expressed by methanolic extract of the stem (MeOH-S). The highest antioxidant capacity and reducing power was shown by MeOH-S and leaf methanolic extract (MeOH-L), respectively. Proficient antibacterial activity was shown by EA-L extract against Bacillus subtilis and Escherichia coli. Remarkable α-amylase and α-glucosidase inhibition potential was expressed by ethyl acetate fruit (EA-F) and n-Hexane leaf (nH-L) extracts, respectively. In case of brine shrimp lethality assay, 41.67% of the extracts (LC50 < 50 µg/mL) were considered as extremely cytotoxic. The test extracts also showed mild antifungal and protein kinase inhibition activities. The present study explores the therapeutic potential of P. roxburghii and calls for subsequent studies to isolate new bioactive leads through bioactivity-guided isolation.

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HPLC-Q-Orbitrap-MS/MS phenolic profiles and biological activities of extracts from roxburgh rose (Rosa roxburghii Tratt.) leaves

Cited by 19 publications

References 34 publications

Free and Bound Phenolic Profiles of Rosa roxburghii Tratt Leaves and Their Antioxidant and Inhibitory Effects on α-Glucosidase

Free and Bound Phenolic Profiles of Rosa roxburghii Tratt Leaves and Their Antioxidant and Inhibitory Effects on α-Glucosidase

PARAFAC modeling of dandelion phenolic compound fluorescence relation to antioxidant properties

HPLC-DAD Based Polyphenolic Profiling and Evaluation of Pharmacological Attributes of Putranjiva roxburghii Wall.

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