HPLC evaluation of water-soluble extracts of Chamaenerion angustifolium L. and Pentaphylloides fruticosa L

Shikov, Alexander N.; Poltanov, Eugeny A.; Pozharitskaya, Olga N.; Dorman, H. J. Damien; Makarov, Valery G.; Тихонов, В. П.; Hiltunen, R.

doi:10.1055/s-2007-987082

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“…The aerial parts of P. fruticosa have been studied extensively and have been found to contain a wide variety of polyphenolics, such as ellagic acid, catechins and flavonols (quercetin, kaempferol and rhamnetin glycosides) [ 19 , 20 , 21 , 22 , 23 , 24 ]. Our results show that P. fructicosa is rich in polyphenolic compounds, and they are consistent with earlier studies on reported by Shikov et al [ 19 ] and Miliauskas et al . [ 20 ].…”

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confidence: 99%

Variation in Total Polyphenolics Contents of Aerial Parts of Potentilla Species and Their Anticariogenic Activity

2010

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The aerial parts of selected Potentilla species (P. anserina, P. argentea, P. erecta, P. fruticosa, P. grandiflora, P. nepalensis, P. norvegica, P. pensylvanica, P. crantzii and P. thuringiaca) were investigated in order to determine their contents of polyphenolic compounds. The results showed that P. fruticosa has relatively high concentrations of tannins (167.3 ± 2.0 mg/g dw), proanthocyanidins (4.6 ± 0.2 mg/g dw) and phenolic acids (16.4 ± 0.8 mg/g dw), as well as flavonoids (7.0 ± 1.1 mg/g dw), calculated as quercetin. Furthermore, we investigated the in vitro inhibitory effects of aqueous extracts from these species against cariogenic Streptococcus spp. strains. It was found that the tested samples moderately inhibit the growth of oral streptococci. However, all the preparations exhibited inhibitory effects on water-insoluble α-(1→3)-, α-(1→6)-linked glucan (mutan) and artificial dental plaque formation. The extract from P. fruticosa showed the highest anti-biofilm activities, with minimum mutan and biofilm inhibition concentrations of 6.25–25 and 50–100 µg/mL, respectively. The results indicate that the studied Potentilla species could be a potential plant material for extracting biologically active compounds, and could become a useful supplement for pharmaceutical products as a new anticariogenic agent in a wide range of oral care products.

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