HPLC-DAD profiles and pharmacological insights of Onobrychis argyrea subsp isaurica extracts

Güler, Gökalp Özmen; Zengin, Gökhan; Karadag, Firat; Mollica, Adriano; Picot, Carene Marie Nancy; Mahomoodally, Mohamad Fawzi

doi:10.1016/j.compbiolchem.2018.07.016

Cited by 7 publications

(6 citation statements)

References 62 publications

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“…Chemical compositions of plants are inherently complex and variable due to a variety of circumstances, including geographical location and environmental conditions. This highlights the significance of employing highly selective, sensitive, and versatile analytical tools for the analysis of complex matrices [5] …”

Section: Resultsmentioning

confidence: 99%

“…isaurica (1254 � 28 μg/g extract). [5] In another study, rutin was found most abundant phenolic compound in Onobrychis viciifolia. [24] Literature survey demonstrated that phytochemical studies are compatible with our findings.…”

Section: Phytochemical Evaluationmentioning

confidence: 93%

“…This highlights the significance of employing highly selective, sensitive, and versatile analytical tools for the analysis of complex matrices. [5] In this study, it was aimed to elucidate the phytochemical profile of OA. First, the quantitative measurement of 53 phenolic and flavonoid components was carried out using an LC-MS/MS system for OAM.…”

Section: Phytochemical Evaluationmentioning

confidence: 99%

“…isaurica was demon-strated their anti-tyrosinase activity for hyperpigmentation. [5,6] Onobrychis argyrea subsp. argyrea (OA), commonly known as 'silvery sainfoin', is a member of Onobrychis Mill.…”

Section: Introductionmentioning

confidence: 99%

“…Also, biological activity studies on O. hypargyrea and O. argyrea subsp. isaurica was demonstrated their anti‐tyrosinase activity for hyperpigmentation [5,6] . Onobrychis argyrea subsp.…”

Section: Introductionmentioning

confidence: 99%

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In vitro Evaluation of Skin Related Enzyme Inhibitory Effect and Emulgel Formulation Development Studies of Onobrychis Argyrea subsp. Argyrea with Phytochemical Analysis

Şentürk,

Barak,

Çağlar

et al. 2024

Chemistry & Biodiversity

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Species of Onobrychis have been used to treat skin disorders such as wounds and cuts in folk medicine and Onobrychis argyrea subsp. argyrea (OA) commonly known as ‘silvery sainfoin’, is a member of this genus. In this study, it was aimed to investigate the skin‐related biological activities and phytochemical characterization of OA. Moreover, an emulgel formulation was developed from the main methanolic extract of the plant (OAM). Initially, to identifiy of the active fractions, aerial parts of the plant material was extracted with methanol and fractionated by n‐hexane, chloroform, ethyl acetate and n‐butanol, respectively. Antioxidant activity was determined by CUPRAC, TOAC, FRAP and DPPH assays. Thereafter, the inhibition potential of OAM, novel formulation and all fractions was measured against elastase, collagenase, tyrosinase and hyaluronidase enzymes. OAM was analyzed and characterized by LC/MS‐MS. The major bioactive flavonoids which are rutin and isoquercetin were measured and compared as qualitative and quantitative via high performance thin layer chromatography (HPTLC) analysis in OAM and fractions. The results showed that extracts of OA can be a potential cosmeceutical agent for skin related problems.

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Section: Resultsmentioning

confidence: 99%

Section: Phytochemical Evaluationmentioning

confidence: 93%

Section: Phytochemical Evaluationmentioning

confidence: 99%

Section: Introductionmentioning

confidence: 99%

“…Also, biological activity studies on O. hypargyrea and O. argyrea subsp. isaurica was demonstrated their anti‐tyrosinase activity for hyperpigmentation [5,6] . Onobrychis argyrea subsp.…”

Section: Introductionmentioning

confidence: 99%

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In vitro Evaluation of Skin Related Enzyme Inhibitory Effect and Emulgel Formulation Development Studies of Onobrychis Argyrea subsp. Argyrea with Phytochemical Analysis

Şentürk,

Barak,

Çağlar

et al. 2024

Chemistry & Biodiversity

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Potential use of wild Onobrychis species for climate change mitigation and adaptation

Sakhraoui,

Ltaeif,

Sakhraoui

et al. 2023

Crop Science

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Climate change is threatening environmental and nutritional security. In this scenario, forage crops and their wild relatives may contribute to maintain ecosystem services and minimize the effects of global warming. We reviewed the literature regarding the ecological, agronomic and nutraceutical values of wild Onobrychis Miller species (sainfoins, Family Fabaceae). We also discuss their application prospect and existing problems hampering their widespread domestication. Wild species of the genus Onobrychis have certain interesting agronomic and ecological features such as perenniality, deep root system and high stress tolerance, which make them suitable for future cultivation under climate change. Wild Onobrychis species are multipurpose species which can be utilized for fodder and honey production under harsh environmental conditions. In addition, wild Onobrychis species exhibit anti‐oxidant, anti‐diabetic, anti‐inflammatory, anti‐tumor, anti‐microbial, anti‐stressor and many other pharmacological effects. Wild Onobrychis species have not been the subject of detailed studies. Compared with the cultivated forage legumes, wild Onobrychis species are still under‐exploited despite their potential to alleviate forage and food insecurity, either by domestication or by providing novel alleles for breeding purposes of the cultivated species Onobrychis viciifolia. Our review aims to increase scientific awareness towards exploring the potential uses of wild Onobrychis species to tackle current climate change.This article is protected by copyright. All rights reserved

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Phytochemical profile by LC-MS/MS analysis and evaluation of antioxidant, antidiabetic, anti-Alzheimer, and anticancer activity of Onobrychis argyrea leaf extracts

Yeniçeri,

Altay,

Koksal

et al. 2024

European Journal of Integrative Medicine

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HPLC-DAD profiles and pharmacological insights of Onobrychis argyrea subsp isaurica extracts

Cited by 7 publications

References 62 publications

In vitro Evaluation of Skin Related Enzyme Inhibitory Effect and Emulgel Formulation Development Studies of Onobrychis Argyrea subsp. Argyrea with Phytochemical Analysis

In vitro Evaluation of Skin Related Enzyme Inhibitory Effect and Emulgel Formulation Development Studies of Onobrychis Argyrea subsp. Argyrea with Phytochemical Analysis

Potential use of wild Onobrychis species for climate change mitigation and adaptation

Phytochemical profile by LC-MS/MS analysis and evaluation of antioxidant, antidiabetic, anti-Alzheimer, and anticancer activity of Onobrychis argyrea leaf extracts

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