HPLC-DAD profile of phenolic compounds and antioxidant activity of leaves extract of Rhamnus alaternus L.

Phenolic Compounds as Nutraceuticals or Functional Food Ingredients

“…PC are currently receiving high attention because of their beneficial health effects, mainly antioxidant [163,164], anti-inflammatory [165,166], antimicrobial [167], cardio-protective [168], cancerpreventive [16] and neuro-protective [169] properties. These compounds assume different forms in the body allowing prevention or treatment of these diseases [170][171][172][173].…”

Effect of Caesalpinia sappan L. extract on physico-chemical properties of emulsion-type pork sausage during cold storage

“…Also, in the study of Safitri, Tarigan, Freisleben, Rumampuk, and Murakami (2003), 1′,4′-dihydrospiro[benzofuran-3(2H),3′-[3H-2]benzopyran]-1′,6′,6′,b7′-tetrol (compound 1) and 3- [[4,5-dihydroxy-2(hydroxymethyl)phenyl]-methyl]-2,3-dihydro-3,6-benzofurandiol (compound 2) from C. sappan possessed similar radical scavenging activities as ascorbic acid, and they were more effective than other well-known antioxidants such as α-tocopherol, β-carotene, and BHT. In addition, phenolic compounds are the major components of plants and contribute to the antioxidative capacity by the scavenging ability of free radicals (Moussi et al, 2015). Furthermore, the main constituents related to the antioxidative capability were protosappanin A, protosappanin B, and brazilein from C. sappan L. (Hu et al, 2008).…”

Rhamnus alaternus Plant: Extraction of Bioactive Fractions and Evaluation of Their Pharmacological and Phytochemical Properties

“…The results of their investigation proved that leaves extracts obtained by maceration were better and more effective than those obtained by decoction in terms of bioactivity. Also, Moussi and colleagues investigated the antioxidant activity of the methanolic extract from R. alaternus leaves and reported that leaves extract from this plant can be used for formulating pharmaceutical products for various diseases [ 48 ]. The composition of R. alaternus roots, bark and leaves extracts was extensively investigated using the maceration method [ 18 , 20 , 22 , 24 , 47 , 50 , 51 , 52 , 55 , 57 , 58 ].…”

“…The phytochemical investigations of Rhamnus alaternus extracts led to the isolation of various classes of natural bioactive compounds, and evidenced the richness in secondary metabolites of this medicinal plant. These bioactive compounds included flavonoids, tannins, anthraquinones, anthocyanins, anthocyanidins, and other compounds [ 48 , 72 ], isolated from various parts of R. alaternus such as barks, leaves, roots, and berries extracts. The investigation of these compounds was limited to qualitative studies.…”

“…More, flavonols such as kaempferol 3-0-β-isorhamninoside, rhamnocitrine 3-0-β-isorhamninoside, and rhamnetin-3-0-isorhamninoside ( Figure S2(13)–(15) ) were also isolated from Rhamnus alaternus’s leaves by Soxhlet extraction method [ 24 , 50 ]. Furthermore, other valuable bioactive compounds were isolated from R. alaternus’ leaves such as kaempferol 3-O acetyl-rhamnoside and quercetin-3-rhamnoside [ 23 , 48 ].…”