2023
DOI: 10.1002/cbdv.202300349
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HPLC and GC Characterization of Dicliptera bupleuroides Aerial Parts and Evaluation of Its Anti‐Inflammatory Potential in Vitro, in silico and in Vivo Using Carrageenan and Formalin Induced Inflammation in Rat Models

Abstract: This study aimed to evaluate the anti‐inflammatory activity of Dicliptera bupleuroides methanol extract (DBM) and its fractions. The samples showed significant inhibition of cyclooxygenase where DBM showed the highest inhibitory potential at 100 µg/mL estimated by 67.86%.. At a 400 mg/kg dose, all the samples showed pronounced results in carrageenan induced acute inflammation in rat model with DBM showed the highest efficiency displaying 65.32% inhibition compared to the untreated rats. Formalin model was also… Show more

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