HPLC Analysis of Tiaprofenic Acid in the Samples of Whole Blood Using L-L and S-L Extractions

Procedures for the determination of individual antioxidants of different nature in biological materials with the use of electrochemical, chromatographic, spectrochemical, and other methods were considered. The main performance characteristics of these procedures are presented. JOURNAL OF ANALYTICAL CHEMISTRY Vol. 60 No. 7 2005 ANTIOXIDANTS AS ANALYTES IN ANALYTICAL CHEMISTRY 601rings, the ortho and para positions of hydroxyl groups, their tert -butyl screening, the formation of semiquinone forms, thiol-containing compounds, the chelation of variable-valence metals, receptor interactions with the cell membrane, etc.

show abstract

“…The procedure was used for the estimation of the physiological and pathological changes caused by the action of medicines [76].…”

Section: Determination Of Low-molecular Bioantioxidantsmentioning

confidence: 99%

Antioxidants As Analytes in Analytical Chemistry

Будников

Ziyatdinova

2005

J Anal Chem

View full text Add to dashboard Cite

show abstract

An enhanced procedure for measuring organic acids and methyl esters in PM<sub>2.5</sub>

Liu¹,

Duan²,

He³

et al. 2015

Preprint

View full text Add to dashboard Cite

Abstract. We have developed an enhanced analytical procedure to measure organic acids and methyl esters in fine aerosol with much greater specificity and sensitivity than previously available. This capability is important because of these species and their low concentrations, even in highly polluted atmospheres like Beijing, China. The procedure first separates the acids and esters from the other organic compounds with anion-exchange solid- phase extraction (SPE), then, quantifies them by gas chromatography coupled with mass spectrometry. This allows us to accurately quantify the C4-C11 dicarboxylic and the C8-C30 monocarboxylic acids. Then the acids are separated from the esters on an aminopropyl SPE cartridge, whose weak retention isolates and enriches the acids from esters prevents the fatty acids and dimethyl phthalate from being overestimated. The resulting correlations between the aliphatic acids and fatty acid methyl esters (FAMEs) suggest that FAMEs had sources similar to those of the carboxylic acids, or were formed by esterifying carboxylic acids, or that aliphatic acids were formed by hydrolyzing FAMEs. In all, 17 aromatic acids were identified and quantified using this procedure coupled with gas chromatography-tandem mass spectrometry, including the five polycyclic aromatic hydrocarbon (PAH) acids 2-naphthoic, biphenyl-4-carboxylic, 9-oxo-9H-fluorene-1-carboxylic, biphenyl-4,4´-dicarboxylic, and phenanthrene-1-carboxylic acid, plus 1,8-naphthalic anhydride. Correlations between the PAH-acids and the dicarboxylic and aromatic acids indicated that the first three acids and 1,8-naphthalic anhydride were mainly secondary, the last two mainly primary.

show abstract

HPLC Analysis of Tiaprofenic Acid in the Samples of Whole Blood Using L-L and S-L Extractions

Cited by 2 publications

References 14 publications

Antioxidants As Analytes in Analytical Chemistry

Antioxidants As Analytes in Analytical Chemistry

An enhanced procedure for measuring organic acids and methyl esters in PM<sub>2.5</sub>

Contact Info

Product

Resources

About

HPLC Analysis of Tiaprofenic Acid in the Samples of Whole Blood Using L-L and S-L Extractions

Cited by 2 publications

References 14 publications

Antioxidants As Analytes in Analytical Chemistry

Antioxidants As Analytes in Analytical Chemistry

An enhanced procedure for measuring organic acids and methyl esters in PM&lt;sub&gt;2.5&lt;/sub&gt;

Contact Info

Product

Resources

About

An enhanced procedure for measuring organic acids and methyl esters in PM<sub>2.5</sub>