Hox Gene Collinearity with Pulling Physical Forces Create a Hox Gene Clustering in Embryos of Vertebrates, Invertebrates, Complete or Split Clutters
Spyros Papageorgiou
Abstract:Hox gene clusters are crucial in Embryogenesis. It was observed that some Hox genes are located in order along the telomeric to centromeric direction of the DNA sequence: Hox1, Hox2, Hox3…. These genes are expressed in the same order in the ontogenetic units of the Drosophila embryo along the Anterior-Posterior axis. The two entities (genome and embryo) differ significantly in linear size and in-between distance. This strange phenomenon was named Spatial Collinearity (SP). Later, it was observed th… Show more
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