How well does ambulatory blood pressure predict target-organ disease and clinical outcome in patients with hypertension?

White, William B.

doi:10.1097/00126097-199912002-00004

Cited by 15 publications

(19 citation statements)

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“…Percent of 24-h records with abnormal circadian BP variability in normoglycemics [1][2][3][4][5][6] and prediabetics [7][8][9][10][11][12] is shown in Figure 1. Overall, 66.7% prediabetics had abnormal circadian BP variations, compared to none in normoglycemics (Po0.001) (Figure 2).…”

Section: Resultsmentioning

confidence: 99%

“…6 A 7-day ABPM delineates abnormal variations including decreased HR variability, excessive pulse pressure, circadian-hyper-amplitude-tension (CHAT), impaired vascular compliance and/or odd circadian BP timing (circadian ecphasia). These conditions have been shown to be independent risk factors for heart disease and stroke, 7,8 even in apparently healthy individuals without chronic disease.…”

Section: Introductionmentioning

confidence: 99%

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Prediabetes is associated with abnormal circadian blood pressure variability

et al. 2008

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Blood pressure (BP) exhibits a circadian variation characterized by a morning increase, followed by a small postprandial valley and a deeper descent during nocturnal rest. Although abnormal 24-h variability (abnormal circadian variability (ACV)) predicts adverse cardiovascular disease (CVD) outcomes, a 7-day automatic ambulatory BP monitoring (ABPM) and subsequent chronobiologic analysis of the gathered data, permits identification of consistency of any abnormal circadian variation. To test whether normal overweight healthy men and women with prediabetes differed from subjects with normoglycemia in having ACV with a 7-day ABPM. Consent for a 7-day ABPM was obtained from subjects with family history of diabetes mellitus, who were participating in the screening phase for a randomized, double blind, placebo-controlled weight loss trial in prediabetics to prevent progression to diabetes mellitus. The automatic 7-day ABPM device recorded BP and heart rate every 30 min during the day and every 60 min during the night. Normoglycemic and prediabetic subjects matched for age, sex, race, BP, BMI, waist circumference and glycemic control, differed statistically significantly only in their fasting and/or 2-h postprandial serum glucose concentrations. Chronobiologically-interpreted 7-day ABPM uncovered no abnormalities in normoglycemics, whereas prediabetics had a statistically significantly higher incidence of high mean BP (MESOR-hypertension), excessive pulse pressure and/or circadian hyper-amplitude-tension (CHAT) (Po0.001). ACV detected with 7-day ABPM may account for the enhanced CVD risk in prediabetes. These findings provide a basis for larger-scale studies to assess the predictive value of 7-day ABPM over the long term.

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Section: Resultsmentioning

confidence: 99%

Section: Introductionmentioning

confidence: 99%

Prediabetes is associated with abnormal circadian blood pressure variability

et al. 2008

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“…Our results were consistent with results by the Coomer et al 8 It could be proposed that haemodialysis has less cardiovascular risk regarding BP characteristics as compared with CAPD at the first day of haemodialysis. However, the circadian BP rhythm, which is reported as another predictor of cardiac mortality, 17,18 is more deteriorated in the first day in haemodialysis patients as compared with CAPD patients.…”

Section: Discussionmentioning

confidence: 95%

“…17,18 Recently, reduced BP diurnal variability has been reported as a risk factor for left ventricular dilatation in haemodialysis patients. 23 In our study, non-dipper patients had higher LVMI than dippers (Figure 1).…”

Section: Discussionmentioning

confidence: 99%

Ambulatory blood pressure monitoring in haemodialysis and continuous ambulatory peritoneal dialysis (CAPD) patients

et al. 2002

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The aim of this study was to compare the results of the 44-h ambulatory blood pressure monitoring (ABPM) data between haemodialysis (HDp) and CAPD patients and to investigate the relation of circadian rhythm in blood pressure (BP) with development of left ventricular hypertrophy. Twenty-two HDp (11 male, 11 female, mean age: 50 ± 17 years) and 24 CAPDp (11 male, 13 female, mean age: 47 ± 15 years) were included. Echocardiographic measurements and ABPM were performed in all study groups. ABPM of the first and second days were analysed separately and compared with CAPDp. Left ventricular hypertrophy was detected in 17 of the 22 HDp (77%) and 17 of the 24 CAPDp (71%). There was no significant differences between HD and CAPDp in respect to 44-h, daytime and night-time systolic and diastolic BP values. Although the course of BP in CAPDp was stable during the 44-h period, systolic and diastolic BP levels on the second day were significantly higher than those of on the first day in HDp (P Ͻ 0.001

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“…The best long-term outcome for hypertensive patients is typically seen when antihypertensive therapy has controlled BP effectively throughout a 24-hour cycle of treatment [31]. However, outcomes trials have for the most part relied on office-based BP determination, an ascertainment technique not ideally suited for the detection of BP differences, either in the later part of the day or during sleep [32].…”

Section: Bp Control and Pleiotropismmentioning

confidence: 99%

Do pleiotropic effects of antihypertensive medications exist or is it all about the blood pressure?

Sica

2007

Curr Cardio Risk Rep

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How well does ambulatory blood pressure predict target-organ disease and clinical outcome in patients with hypertension?

Cited by 15 publications

References 0 publications

Prediabetes is associated with abnormal circadian blood pressure variability

Prediabetes is associated with abnormal circadian blood pressure variability

Ambulatory blood pressure monitoring in haemodialysis and continuous ambulatory peritoneal dialysis (CAPD) patients

Do pleiotropic effects of antihypertensive medications exist or is it all about the blood pressure?

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