How we use angiopoietin‐2 in the diagnosis and management of vascular anomalies
Elissa R. Engel,
Timothy D. Le Cras,
Kiersten W. Ricci
Abstract:The diagnosis of vascular anomalies remains challenging due to significant clinical heterogeneity and uncertain etiology. Evaluation using biopsy and/or genetic testing for somatic variants is invasive, expensive, and prone to sampling error. There is great need for noninvasive and easily measured blood laboratory biomarkers that can aid not only in diagnosis, but also management of treatments for vascular anomalies. Angiopoietin‐2, a circulating blood angiogenic factor, is highly elevated in patients with kap… Show more
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