How Useful Are Blood and Stool Biomarkers for Detecting Subclinical Mucosal Inflammation in Ulcerative Colitis?

Role of HMGB1 as a Suitable Biomarker of Subclinical Intestinal Inflammation and Mucosal Healing in Patients with Inflammatory Bowel Disease

“…31,32 Thus, it would be very welcome the availability of readily measured markers able to detect clinically evident and subclinical inflammation of the gut mucosa. Evidence is now accumulating that even a subclinical, other than a severe, intestinal inflammation may cause severe cell damage, providing a common ground in which either cancer or other disorders may develop.…”