How to recognize a trustworthy clinical practice guideline

Abstract

Trustworthy clinical practice guidelines represent a fundamental tool to summarize relevant evidence regarding a set of clinical choices and provide guidance for making optimal clinical decisions. Clinicians must differentiate between guidelines that provide trustworthy evidence guidance and those that do not. We present six questions clinicians should ask when evaluating a guideline’s trustworthiness. (1) Are the recommendations clear?; (2) Have the panelists considered all alternatives?; (3) Have the panelists considered all patient-important outcomes?; (4) Is the recommendation based on an up-to-date systematic review?; (5) Is the strength of the recommendation compatible with the certainty of the evidence?; (6) Might conflicts of interest influence the recommendations? If yes, were they managed? Once the conclude they are dealing with a trustworthy guideline, clinicians must gain an understanding of the transparent evidence summary that the guideline will offer, and judge the applicability of trustworthy recommendations to their patients and settings. Consideration of the circumstances and values and preferences of patients will be crucial for all weak or conditional recommendations.

Adherencia a recomendaciones basadas en evidencia para enfermedades crónicas no transmisibles: estudio de corte transversal multicéntrico en médicos de Bogotá

“…Clinical practice guidelines (CPGs) constitute a tool through which to apply the scientific evidence gathered about CNCDs (8)(9)(10). The objective of CPGs, as compiled from evidence-based recommendations, is to improve clinical outcomes, avoid unjustified variability in clinical practice, implement health resources more efficiently, and reduce inequity gaps (9,11). Consistently, greater adherence of users to CPG has improved clinical outcomes and reduced health costs in CNCD patients (12)(13)(14)(15)(16).…”