How to name it: a rare case of odontogenic cyst

Abstract

Odontogenic cysts and tumors are well-recognized entities to the specialist oral pathologist and they seldom pose problems in differential diagnosis. This paper deals with an aggressive cystic lesion in the maxilla of a 65-year-old male that was characterized by a large radiographically multilocular lesion and a multicystic pattern microscopically. The categorization of this lesion was complicated by the presence of features suggestive of both glandular odontogenic cyst and cystic ameloblastoma with aggressive histologic phenotypes.

Glandular Odontogenic Cyst Associated With Ameloblastoma: Case Report and Review of the Literature

“…The current case was on the left side of the jaw. In the maxilla, the reported case was located between the left central incisor to the right first molar (15). All four cases and the current case presented with extensive swelling and expansion, and three cases presented with pain (13)(14)(15).…”

“…Only four such cases exist in the literature making the current case only the fifth to be reported. A review of the literature is presented in table 1, summarizing the clinical and radiographic presentation of all five cases (4,(13)(14)(15). Clinically, three of the four cases occurred in the pos-terior mandible extending anteriorly (4,13,14), and one occurred in the posterior maxilla, again extending anteriorly (15).…”

“…The connection between unicystic ameloblastoma and GOC has not been well established given the rarity of the condition. So far, only four cases of GOC are reported to be associated with ameloblastoma (4,(13)(14)(15). None of the four reports have clearly defined the type of ameloblastoma present within the GOC lesion, but at least three point to unicystic ameloblastoma (4,13,14).…”

Report of Two Cases of Combined Odontogenic Tumors: Ameloblastoma with Odontogenic Keratocyst and Ameloblastic Fibroma with Calcifying Odontogenic Cyst

“…Unfortunately, no follow-up data is available for our cases. Many authors believe that hybrid odontogenic lesions are not a result of collision between two distinct entities but rather due to the pluripotentiality of the odontogenic epithelium with both lesions likely developing from a common source or ameloblastomatous change in an existing odontogenic cyst [10][11][12]. We feel this is likely of the ameloblastoma with COC; however, the ameloblastoma with OKC appears to be two distinct entities arising nearly in the same location.…”

“…We have compiled the reported cases, excluding ours, into a table which serves as an updated version similar to Lin et al's (Table 1) [9][10][11][12][13][14][15][16][17][18][19][20][21][22][23]. Information in the table includes location, sex, age, treatment, and any follow-up data.…”