How to Manage Kidney Transplant Recipients: Deciding Between Glomerular Filtration Rate-Estimating Equations, Creatinine Clearance and Albumin-Creatinine Ratio, or Albumin Excretion

López-Pelayo, Iratxe; Blanca, María Auxiliadora Mazuecos; Palacios, M.V. García; Sánchez, Fátima Galán; Rodríguez, Florente López; García, María Ángeles Bailén

doi:10.6002/ect.2017.0335

Cited by 4 publications

(2 citation statements)

References 4 publications

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“…The clearance of sCr was calculated with the formula: MDRD = GFR (mL/min × 1.73 m 2 ) = 186 × CrS − 1.154 × (age) − 0.203 × (0.742 in case of being a woman)[ 24 ].…”

Section: Methodsmentioning

confidence: 99%

The Effect of Enalapril, Losartan, or Not Antihypertensive on the Oxidative Status in Renal Transplant Recipients

Andrade‐Sierra

Morales-Guillén

García-Sánchez

et al. 2022

Oxidative Medicine and Cellular Longevity

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The clinical and biochemical improvement observed in kidney transplant (RT) recipients is remarkable. The correct functioning of the allograft depends on various factors such as the donor’s age, the alloimmune response, the ischemia-reperfusion injury, arterial hypertension, and the interstitial fibrosis of the allograft, among others. Antihypertensive drugs are necessary for arterial hypertension patients to avoid or reduce the probability of affecting graft function in RT recipients. Oxidative stress (OS) is another complex pathophysiological process with the ability to alter posttransplant kidney function. The study’s objective was to determine the effect of the administration of Enalapril, Losartan, or not antihypertensive medication on the oxidative state in RT recipients at the beginning of the study and one year of follow-up. All patients included in the study found significant overexpression of the oxidative damage marker to DNA and the antioxidant enzymes superoxide dismutase (SOD) and glutathione peroxidase (GPx). In contrast, it was found that the determination of the total antioxidant capacity decreased significantly in the final determination at one year of follow-up in all the patients who ingested Enalapril and Losartan. We found dysregulation of the oxidative state characterized mainly by oxidative damage to DNA and a significant increase in antioxidant enzymes, which could suggest a compensatory effect against the imbalance of the oxidative state.

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“…The clearance of sCr was calculated with the formula: MDRD = GFR (mL/min × 1.73 m 2 ) = 186 × CrS − 1.154 × (age) − 0.203 × (0.742 in case of being a woman)[ 24 ].…”

Section: Methodsmentioning

confidence: 99%

The Effect of Enalapril, Losartan, or Not Antihypertensive on the Oxidative Status in Renal Transplant Recipients

Andrade‐Sierra

Morales-Guillén

García-Sánchez

et al. 2022

Oxidative Medicine and Cellular Longevity

View full text Add to dashboard Cite

show abstract

“…Studies evaluating the validity of ACR 30 mg/g (ACR with a 30-mg/g cutoff) in diagnosing moderate albuminuria in the general population and cohorts with diabetes mellitus and CKD showed that sensitivity ranged between 64% and 94%. 30 , 36 , 66 , 67 , 68 The relatively low sensitivity of ACR using a 30-mg/g cutoff results from insufficient accuracy. Fotheringham et al, 30 measuring accuracy in terms of the percentage of individuals with ACR measurements within 30% of the measured AER, showed that only 49% and 38% of participants in the CRIC and Diabetes Control and Complications Trial (DCCT) studies, respectively, had ACR values within this range.…”

Section: Consequences Of Biases On the Performance Of Acr In Diagnosi...mentioning

confidence: 99%

Measuring Albuminuria in Individuals With Obesity: Pitfalls of the Urinary Albumin-Creatinine Ratio

Chagnac,

Friedman

2024

Kidney Medicine

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Creatinine clearance rate predicts prognosis of patients with systemic lupus erythematosus: a large retrospective cohort study

Jin

Feng

et al. 2020

Clin Rheumatol

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How to Manage Kidney Transplant Recipients: Deciding Between Glomerular Filtration Rate-Estimating Equations, Creatinine Clearance and Albumin-Creatinine Ratio, or Albumin Excretion

Cited by 4 publications

References 4 publications

The Effect of Enalapril, Losartan, or Not Antihypertensive on the Oxidative Status in Renal Transplant Recipients

The Effect of Enalapril, Losartan, or Not Antihypertensive on the Oxidative Status in Renal Transplant Recipients

Measuring Albuminuria in Individuals With Obesity: Pitfalls of the Urinary Albumin-Creatinine Ratio

Creatinine clearance rate predicts prognosis of patients with systemic lupus erythematosus: a large retrospective cohort study

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