How to engineer superhydrophobic micromechanical sensors preserving mass resolution

Borin, Daniele; Melli, Mauro; Zilio, Simone Dal; Toffoli, Valeria; Scoles, G.; Toffoli, Giuseppe; Lazzarino, Marco

doi:10.1016/j.snb.2014.02.108

Cited by 7 publications

(7 citation statements)

References 25 publications

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“…Analytical devices, called sensors, consist of a transducer and recognition elements to capture an analyte for their structure evaluation and they act by modifying the responses into the signals. The sensors can be classified as optical [73,74,75], electrochemical [76,77,78], piezoelectric [79,80,81], magnetic [82,83,84], micromechanical [85,86,87] and thermal [88,89,90] sensors.…”

Section: Molecularly Imprinted Polymer Based Sensorsmentioning

confidence: 99%

Molecularly Imprinted Polymer Based Sensors for Medical Applications

Saylan

Akgönüllü

Yavuz

et al. 2019

Sensors

220

106

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Sensors have been extensively used owing to multiple advantages, including exceptional sensing performance, user-friendly operation, fast response, high sensitivity and specificity, portability, and real-time analysis. In recent years, efforts in sensor realm have expanded promptly, and it has already presented a broad range of applications in the fields of medical, pharmaceutical and environmental applications, food safety, and homeland security. In particular, molecularly imprinted polymer based sensors have created a fascinating horizon for surface modification techniques by forming specific recognition cavities for template molecules in the polymeric matrix. This method ensures a broad range of versatility to imprint a variety of biomolecules with different size, three dimensional structure, physical and chemical features. In contrast to complex and time-consuming laboratory surface modification methods, molecular imprinting offers a rapid, sensitive, inexpensive, easy-to-use, and highly selective approaches for sensing, and especially for the applications of diagnosis, screening, and theranostics. Due to its physical and chemical robustness, high stability, low-cost, and reusability features, molecularly imprinted polymer based sensors have become very attractive modalities for such applications with a sensitivity of minute structural changes in the structure of biomolecules. This review aims at discussing the principle of molecular imprinting method, the integration of molecularly imprinted polymers with sensing tools, the recent advances and strategies in molecular imprinting methodologies, their applications in medical, and future outlook on this concept.

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Section: Molecularly Imprinted Polymer Based Sensorsmentioning

confidence: 99%

Molecularly Imprinted Polymer Based Sensors for Medical Applications

Saylan

Akgönüllü

Yavuz

et al. 2019

Sensors

220

106

View full text Add to dashboard Cite

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“…Details of the fabrication procedure are reported elsewhere (Borin et al 2014). Briefly, we started from a well cleaned Si(100) wafer.…”

Section: 1pillars Fabricationmentioning

confidence: 99%

“…In order to achieve permanent superhydrophobic properties (Cassie-Baxter state), pillar walls were coated with a hydrophobic layer as discussed in detail in (Borin et al 2014). In particular we formed an alkanosilane coating through octadecyltrichlorosilane (OTS) deposition from a 1mM solution in dry toluene for 1h.…”

Section: Pillars Hydrophobizationmentioning

confidence: 99%

See 1 more Smart Citation

Parallel optical read-out of micromechanical pillars applied to prostate specific membrane antigen detection

Tardivo

Toffoli

Fracasso

et al. 2015

Biosensors and Bioelectronics

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“…There is a large and emerging demand for the use of Micro Electro Mechanical Systems (MEMS) working in aqueous environments, especially for biosensors and biotechnology applications. Applications span from general purpose devices, like Atomic Force Microscopy (AFM) probes used in liquid environment [1] to highly specialized devices exploiting horizontal cantilevers or vertical micropillars [2][3] used for the detection of the biomolecule of interest in the analyte solution [4]. In all these cases, the devices are obtained from silicon or silicon derivatives (e.g.…”

Section: Introductionmentioning

confidence: 99%