How to Design Both Mechanically Strong and Self-Healable Hydrogels?

Okay, Oğuz

doi:10.1007/12_2019_53

Cited by 13 publications

(8 citation statements)

References 142 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…Unlike traditional hydrogels, self-healing hydrogel forms a spatial network through dynamic connectivity. Recently, selfhealing hydrogels have attracted extensive research interest and have been applied to constructing various new intelligent materials [96]. Injection of self-healing hydrogels can deliver drugs in vivo without significant damage to the body since the hydrogels are embedded without surgical incision [97].…”

Section: Intelligent Materialsmentioning

confidence: 99%

Poly(vinyl alcohol) Hydrogels: The Old and New Functional Materials

Wang

Bai

Shao

et al. 2021

International Journal of Polymer Science

View full text Add to dashboard Cite

Hydrogels have three-dimensional network structures, high water content, good flexibility, biocompatibility, and stimulation response, which have provided a unique role in many fields such as industry, agriculture, and medical treatment. Poly(vinyl alcohol) PVA hydrogel is one of the oldest composite hydrogels. It has been extensively explored due to its chemical stability, nontoxic, good biocompatibility, biological aging resistance, high water-absorbing capacity, and easy processing. PVA-based hydrogels have been widely investigated in drug carriers, articular cartilage, wound dressings, tissue engineering, and other intelligent materials, such as self-healing and shape-memory materials, supercapacitors, sensors, and other fields. In this paper, the discovery, development, preparation, modification methods, and applications of PVA functionalized hydrogels are reviewed, and their potential applications and future research trends are also prospected.

show abstract

Section: Intelligent Materialsmentioning

confidence: 99%

Poly(vinyl alcohol) Hydrogels: The Old and New Functional Materials

Wang

Bai

Shao

et al. 2021

International Journal of Polymer Science

View full text Add to dashboard Cite

show abstract

“…This increase in toughness can be attributed to the coexistence of crystalline domains and hydrophobic associations in the hydrogels. The brittle C16 crystals microscopically fracture at the yield point by dissipating energy, while the hydrophobic associations acting as weak cross-links keep the hydrogel sample together. ,, This mechanism of toughness improvement is similar to the double-network hydrogels composed of ductile and brittle networks . The hydrogel with 20 mol % C16A exhibits a modulus of 23 ± 3 MPa, 7.31 ± 0.36 MJ/m 3 of toughness and sustains 3.4 ± 0.4 MPa stresses at 281 ± 36% elongation, which verifies its soft and pliable mechanical behavior (Figures a, b).…”

Section: Resultsmentioning

confidence: 69%

4D Printing of Body Temperature-Responsive Hydrogels Based on Poly(acrylic acid) with Shape-Memory and Self-Healing Abilities

Abdullah

Okay

2023

ACS Appl. Bio Mater.

Self Cite

View full text Add to dashboard Cite

Additive manufacturing of smart materials that can be dynamically programmed with external stimuli is known as 4D printing. Among the 4D printable materials, hydrogels are the most extensively studied materials in various biomedical areas because of their hierarchical structure, similarity to native human tissues, and supreme bioactivity. However, conventional smart hydrogels suffer from poor mechanical properties, slow actuation speed, and instability of actuated shape. Herein, we present 4D-printed hydrogels based on poly(acrylic acid) that can concurrently possess shape-memory and self-healing properties. The printing of the hydrogels is achieved by solvent-free copolymerization of the hydrophilic acrylic acid (AAc) and hydrophobic hexadecyl acrylate (C16A) monomers in the presence of TPO photoinitiator using a stereolithography-based commercial resin printer followed by swelling in water. The printed hydrogels undergo a reversible strong-to-weak gel transition below and above human body temperature due to the melting and crystallization of the hydrophobic C16A domains. In this way, the shape-memory and self-healing properties of the hydrogels can be magically actuated near the body temperature by adjusting the molar ratio of the monomers. Furthermore, the printed hydrogels display a high Young’s modulus (up to ∼215 MPa) and high toughness (up to ∼7 MJ/m3), and their mechanical properties can be tuned from brittle to ductile by reducing the molar fraction of C16A, or the deformation speed. Overall, the developed 4D printable hydrogels have great potential for various biomedical applications.

show abstract

“…The most effective design principle was based on constructing a potential energy dissipation model in the gel matrix by maneuvering sacrificial or reversible bonds that avert crack extension and damage under strain. Second-generation hydrogels with high Young’s modulus and tensile strengths have been developed by modifying the gel network structure to induce energy dissipative mechanisms at the molecular level 10 . Several smart and effective techniques have already been employed to increase the mechanical strength of hydrogels keeping all other desirable properties unchanged.…”

Section: Introductionmentioning

confidence: 99%

Effect of sizes of vinyl modified narrow-dispersed silica cross-linker on the mechanical properties of acrylamide based hydrogel

Karim

Harun‐Ur‐Rashid

Imran

2023

Sci Rep

View full text Add to dashboard Cite

Polymeric hydrogel with the incorporation of nano to submicro-meter sized materials forms an exhilarating new generation of composite hydrogels. Most of the applications of hydrogels are in aqueous environments in which they swell to a very high degree. This emanates from low density of the polymer chains, making them highly inferior in terms of physical strength and their prospective applications. In order to address the weak mechanical properties, hydrogels have successfully prepared with high tensile strength and toughness by reinforcing the acrylamide (AAm) network with 3-methacryloxypropyltrimethoxysilane (MPTS) modified silica particles (MSiO2) as chemical cross-linker. The MSiO2 cross-linkers are prepared from narrow-dispersed silica particles (SiO2) of 100 nm, 200 nm, and 300 nm diameters to investigate the effect of cross-linker sizes on the mechanical strengths of hydrogels. The presence of MSiO2 remarkably increases the stretching ability and toughness of hydrogels compared to conventional hydrogels. The tensile strength, toughness, and Young’s modulus of the hydrogel decrease from 30 to 11 kPa, 409 to 231 kJ/m3, and 0.16 to 0.11 kPa, respectively, while the SiO2 particle size increase from 100 to 300 nm and the concentration of AAm and MSiO2 (%) are kept constant. The compressive strength and toughness of the hydrogel decrease from 34 to 18 kPa and 6 to 4 kJ/m3, respectively, but the Young’s modulus increases from 0.11 to 0.19 kPa. This work is excellent proof of regulating mechanical strength of hydrogel by adjusting the particle size of MSiO2 cross-linkers.

show abstract

How to Design Both Mechanically Strong and Self-Healable Hydrogels?

Cited by 13 publications

References 142 publications

Poly(vinyl alcohol) Hydrogels: The Old and New Functional Materials

Poly(vinyl alcohol) Hydrogels: The Old and New Functional Materials

4D Printing of Body Temperature-Responsive Hydrogels Based on Poly(acrylic acid) with Shape-Memory and Self-Healing Abilities

Effect of sizes of vinyl modified narrow-dispersed silica cross-linker on the mechanical properties of acrylamide based hydrogel

Contact Info

Product

Resources

About