How to appropriately choose observed indexes

Hu, Lianxi; Bao, Xiao-lei; Guan, Xue; Wang, Qi

doi:10.3736/jcim20110505

Cited by 1 publication

(1 citation statement)

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“…It has been reported that some tannins have beneficial effects such as anticancer , antimicrobial , and anti‐AIDS activities . However, there is growing evidence that tannins, especially when injected, produce adverse effects in humans such as jaundice, liver putrescence , and accelerated agglomeration or hemolysis of erythrocytes . Quantification and control of tannin content in TCMI have therefore received much attention.…”

Section: Introductionmentioning

confidence: 99%

Online solid‐phase extraction with high‐performance liquid chromatography and mass spectrometry for the determination of five tannins in traditional Chinese medicine injections

Sun

Lin

Jie

et al. 2016

J of Separation Science

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A rapid analytical method based on online solid-phase extraction with high-performance liquid chromatography and mass spectrometry has been established and applied to the determination of tannin compounds that may cause adverse effects in traditional Chinese medicine injections. Different solid-phase extraction sorbents have been compared and the elution buffer was optimized. The performance of the method was verified by evaluation of recovery (≥40%), repeatability (RSD ≤ 6%), linearity (r(2) ≥ 0.993), and limit of quantification (≤0.35 μg/mL). Five tannin compounds, gallic acid, cianidanol, gallocatechin gallate, ellagic acid, and penta-O-galloylglucose, were identified with concentrations ranging from 3.1-37.4 μg/mL in the analyzed traditional Chinese medicine injections.

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Section: Introductionmentioning

confidence: 99%