How to accelerate the upper urinary stone discharge after extracorporeal shockwave lithotripsy (ESWL) for &lt; 15 mm upper urinary stones: a prospective multi-center randomized controlled trial about external physical vibration lithecbole (EPVL)

Zhou, Yang; Tang, Fucai; Xu, Chunbao; Gu, Xiaoqing; Chen, Xuehua; Wang, Rongjiang; Yan, Jiaka; Wang, Xiang; Gao, Wenjing; Hou, Chenliang; Guo, Jianming; Zhang, Jian; Gurioli, Alberto; Ye, Zhangqun; Zeng, Guohua

doi:10.1007/s00345-017-2123-4

Cited by 19 publications

(13 citation statements)

References 28 publications

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“…However, there still lack reported studies showing the precise effect of EPVL treatment after ESWL therapy for upper ureteric stones 1.0-2.0 cm in size. Although, in their other study [27] they evaluated the efficacy of EPVL in patients with upper ureteric stones, the sample size was relatively small compared with our center. Therefore, we conducted this prospective, randomized study in our center.…”

Section: Discussionmentioning

confidence: 94%

External physical vibration lithecbole facilitating the expulsion of upper ureteric stones 1.0–2.0 cm after extracorporeal shock wave lithotripsy: a prospective randomized trial

et al. 2018

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To observe the efficacy and safety of External Physical Vibration Lithecbole (EPVL) in patients with upper ureteric stones 1.0-2.0 cm after extracorporeal shock wave lithotripsy (ESWL). A total of 271 patients with upper ureteric stones 1.0-2.0 cm were prospectively randomized into two groups. One hundred and twenty-seven cases in the treatment group accepted EPVL therapy and 144 cases as control after ESWL. The stone expulsion status and stone-free rates (SFRs) between two groups were compared at the 1st, 2nd and 4th weekends by imaging examinations. All of 271 patients were randomly assigned to two groups, of which 127 patients were included in the treatment group and 144 in the control group. EPVL was successful in assisting the discharge of stone fragments. The rate of stone expulsion at day 1 in the treatment group was significantly higher than in the control group (79.5% vs. 64.6%, P = 0.006). The SFRs of the 1st weekend (76.3% vs. 61.8%, P = 0.010), the 2nd weekend (88.2% vs. 77.1%, P = 0.017) and the 4th weekend (92.1% vs. 84.0%, P = 0.042) in the treatment group were all significantly higher than that in the control group. However, no statistical significance was found in complications between the two groups (P > 0.05). Furthermore, in the treatment group the patients were treated a mean 4.3 sessions of EPVL. EPVL and ESWL are ideal complementary partners in the treatment of upper ureteric stones 1.0-2.0 cm, satisfying both high SFR and low complication. This method is safe and reproducible in clinical practice, and it also needs large-scale multicenter prospective studies further to prove the above conclusions.

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Section: Discussionmentioning

confidence: 94%

External physical vibration lithecbole facilitating the expulsion of upper ureteric stones 1.0–2.0 cm after extracorporeal shock wave lithotripsy: a prospective randomized trial

et al. 2018

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“…It is very clear and concise that for any newly designed and introduced technique to be well accepted, it should be first safe and also efficacious. Related with this issue, data obtained from several clinical studies have proved well with high-level evidence that the EPVL is a safe, simple, effective, and non-invasive method to facilitate the spontaneous passage of the residual fragments detected after RIRS or ESWL [2][3][4][5][6]. Of the published data with this system so far, Wu et al [2] were able to demonstrate that EVPL as a supplement to RIRS could be more effective than RIRS alone by shortening the time period for stone clearance, increasing complete stone-free rates with good patient compliance and acceptance.…”

mentioning

confidence: 82%

“…Further supporting these findings, Zhang et al [5] were able to show that the best time to perform EPVL is 3 days after RIRS procedure for the highest stone-free rates at any point in time with meaningfully reduced complications caused by these fragments. Last but not least, in their original studies, Long et al [3], Wu et al [6], and Tao et al [4], all reported well that EPVL could facilitate the spontaneous discharge of residual stone fragments with a meaningfully shortened expulsion time after SWL. Thus all these data clearly indicate that the EPVL system can be regarded as an adjunctive active treatment modality particularly for residual stone fragments after RIRS and SWL procedures in an outpatient service manner.…”

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confidence: 98%

Effective and quick discharge of residual fragments after minimal invasive stone procedures with “EPVL” modality: a new and promising approach

Sarıca

2020

Urolithiasis

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“…As listed in Table 1, a total of 8 prospective studies published from 2001 to 2019 were finally enrolled into the present analysis [29,[32][33][34][35][36][37][38], including 7 RCTs and 1 prospective case control study. Three studies were multi-center studies (NCT02645708, NCT02643134, one not registered).…”

Section: Characteristics and Quality Of The Included Studiesmentioning

confidence: 99%

Is physical therapy effective following extracorporeal shockwave lithotripsy and retrograde intrarenal surgery: a meta-analysis and systematic review

2020

Self Cite

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Background: Physical therapy, including percussion, inversion, vibration and combinations, was clinically performed to improve the stone free rate (SFR) following lithotripsy procedures. However, physical therapy is not widely accepted in clinical practice owing to lack of high level evidence support and a standard protocol. The present meta-analysis aimed to evaluate the efficacy and safety of physical therapy in improving SFR following extracorporeal shockwave lithotripsy (ESWL) and retrograde intrarenal surgery (RIRS). Methods: Systematic review of literature from PubMed, Scopus, Cochrane library and Embase was performed in March 2019. The efficacy and safety of physical therapy after ESWL and RIRS were assessed by meta-analysis of SFR and complication rate. Results: A total of 8 prospective studies with 1065 patients were enrolled. When compared to non-intervention, physical therapy provided a higher SFR (OR:3.38, 95% CI: 2.45-4.66, p < 0.0001) at all time points (week 1, week 2 and month 1), while there was no significant difference in complications such as hematuria, lumbago, dizziness and urinary tract infection (OR: 0.84; 95%CI: 0.62-1.13; p = 0.237). In subgroup analysis of different stone locations, lower calyx stone (OR: 3.51; 95%CI: 2.21-5.55; p < 0.0001), upper ureter and renal pelvic stones (OR:2.79; 95%CI:1.62-4.81; p = 0.0002) had a higher SFR after physical therapy, while there was no significant improvement in SFR in upper and middle calyx stones. In subgroup analysis of different techniques, EPVL (external physical vibration lithecbole, OR:3.47; 95%CI:2.24-5.37; p < 0.0001) and PDI (percussion, diuresis and inversion, OR:3.24; 95%CI:2.01-5.21; p < 0.0001) were both effective in improving SFR when compared to non-intervention. Conclusions: Physical therapy is effective in improving the SFR after ESWL and RIRS, especially for lower calyx stones, upper ureter and renal pelvic stones, while without significant side effects. External physical vibration lithecbole (EPVL) might provide a relative uniformed and repeatable protocol for clinical practice of physical therapy.

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How to accelerate the upper urinary stone discharge after extracorporeal shockwave lithotripsy (ESWL) for < 15 mm upper urinary stones: a prospective multi-center randomized controlled trial about external physical vibration lithecbole (EPVL)

Abstract: EPVL is a noninvasive, effective, and safe adjunctive treatment which increases and accelerates upper urinary stones discharge after ESWL treatment.

Cited by 19 publications

References 28 publications

External physical vibration lithecbole facilitating the expulsion of upper ureteric stones 1.0–2.0 cm after extracorporeal shock wave lithotripsy: a prospective randomized trial

External physical vibration lithecbole facilitating the expulsion of upper ureteric stones 1.0–2.0 cm after extracorporeal shock wave lithotripsy: a prospective randomized trial

Effective and quick discharge of residual fragments after minimal invasive stone procedures with “EPVL” modality: a new and promising approach

Is physical therapy effective following extracorporeal shockwave lithotripsy and retrograde intrarenal surgery: a meta-analysis and systematic review

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