Abstract:Treatment of HIV-1 infection with combined antiretroviral therapy substantially improves survival and quality of life, but is associated with metabolic disturbances such as insulin resistance, dyslipidemia and body fat partitioning disorders. These metabolic complications in the setting of suppression of viral replication are associated with increased observed risk for Type 2 diabetes mellitus. Disorders of glucose metabolism present additional challenges in the management of HIV infection, including the long-… Show more
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