Work-life balance, job stress, reward system and turnover intention are some essential elements in a working environment. To a certain extent, some of these elements are prerequisites to job performance. Talent retention is of particular concern to any organization due to globalization, the skills shortage and rapidly advancing technology. Work-life balance represents the dynamic between working life and personal life. Meanwhile job stress requires the employees to resolve job conflict, as unresolved job stress might lead to unproductive results. Reward system is positive outcomes that are earned as a result of an employee's performance. Lastly, turnover intention can be defined as employee's thoughts of quitting their job and an intention to seek out another job outside of the organization. Employee turnover has significant costs and negative consequences for organizations. Far from being a liability, the greatest asset any business has is its employees. And like any asset, employees and talents need to be invested in. However, current statistics show voluntary turnover was the highest among manufacturing workers in Malaysia as compared to other industry. Therefore, the main objective of this study was to investigate the effects of work-life balance, job stress, and reward system towards employees' turnover intention. This study involved 100 respondents from two different factories of a manufacturing company located in Klang Valley, Malaysia. The respondents were randomly selected from various departments. Results indicated that job stress was the most significant factor of employees' intention to quit, followed by the reward system. The implication of this study is that organization should take appropriate action in managing their employees' stress as well as offering an attractive rewards in order to retain their talented staffs hence maintaining the company's stability and competitiveness. Future research should include other factors like organizational politics and downsizing that might influence the turnover intention.