How innovative drug delivery devices can help realize clinical utility of new effective therapies

Lamprou, Dimitrios A.; Singh, Thakur Raghu Raj; Larrañeta, Eneko; Donnelly, Ryan F.

doi:10.1080/17425247.2019.1689956

Cited by 3 publications

(1 citation statement)

References 18 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…Some important characteristic changes involved in microscale manipulation of fluids are given in Table II [64]. Microfluidics also holds significance and its application in fields of nanomedicine (new medicines at nano particles scale containing the biologics like peptide, proteins etc., and other drug molecules), drug delivery, and most prominently in the field of diagnostics [65].…”

Section: A Microfluidics/pcr Testingmentioning

confidence: 99%

MEMS Sensors for Diagnostics and Treatment in the Fight Against COVID-19 and Other Pandemics

et al. 2021

View full text Add to dashboard Cite

As the world is going through an existential global health crisis, i.e., the outbreak of novel coronavirus-caused respiratory disease , the healthcare systems of all the countries require readily available, low cost and highly precise equipment for the rapid diagnostics, monitoring, and treatment of the disease. The performance and precision of this equipment are solely dependent on the sensors being used. The advancement in research and development of micro-electro-mechanical systems (MEMS) based sensors during recent years, has resulted in the improvement of the conventional equipment being used in biomedical and health care applications. Microfluidics (Lab-on-a-chip) and MEMS sensors are now being used extensively for quick and accurate detection, progression monitoring, and treatment of various diseases including Covid-19. The ongoing miniaturization and design improvements have resulted in more precise sensors and actuators for healthcare applications, even for micro and nanoscale measurements in drug delivery and other invasive applications. This article aims at reviewing the MEMS sensors being used or which can be used in the important equipment for the detection and treatment of Covid-19 or other pandemics. An insight into various designs and working principles of the research-based and commercially available MEMS sensors is presented. The study highlights the role and importance of MEMS sensors in the improvement of equipment with conventional sensors. MEMS sensors outperform the conventional sensors due to their small size (1µm-1mm), negligible weight, prompt response, precise measurements, portability, and ease of integration with electronic circuitry.

show abstract

Section: A Microfluidics/pcr Testingmentioning

confidence: 99%

MEMS Sensors for Diagnostics and Treatment in the Fight Against COVID-19 and Other Pandemics

et al. 2021

View full text Add to dashboard Cite

show abstract

Electrospun polymers: Using devices to enhance their potential for biomedical applications

Mao

Wen

et al. 2023

Reactive and Functional Polymers

View full text Add to dashboard Cite

Emerging technologies for diagnostics and drug delivery in the fight against COVID-19 and other pandemics

Lamprou

2020

Expert Review of Medical Devices

Self Cite

View full text Add to dashboard Cite

Introduction: A pandemic is the worst-case scenario in the field of infectious diseases. Innovative technologies have the potential to address the challenges associated with the manufacture of personalized drug delivery systems, biosensors, and medical devices during a pandemic. 3D-Printing, microfluidics, and Microelectromechanical systems (MEMS) can provide an important part on this fight, as are cheap, easy to be operated, capable to provide rapid detection and monitoring of a disease, and deliver medicines.Areas covered: This manuscript answers the question of how these emerging technologies can save lives during a pandemic by avoiding supply chain delays and also by providing rapid diagnostics, disease monitoring, or by offering personalized treatments. The manuscript covers recent approaches in the topic with a focus in manuscripts published in the last year and by emphasising recent regulatory considerations by regulatory agencies in the manufacturing of 3DP systems or other medical devices during COVID. Expert opinion: New manufacturing techniques are emerging with the ability to address the challenges associated with the development of medical devices or diagnostics, during a pandemic. Are many challenges in order to achieve this and especially in short times that are required under a pandemic attack, which will also be covered in this manuscript.

show abstract

How innovative drug delivery devices can help realize clinical utility of new effective therapies

Cited by 3 publications

References 18 publications

MEMS Sensors for Diagnostics and Treatment in the Fight Against COVID-19 and Other Pandemics

MEMS Sensors for Diagnostics and Treatment in the Fight Against COVID-19 and Other Pandemics

Electrospun polymers: Using devices to enhance their potential for biomedical applications

Emerging technologies for diagnostics and drug delivery in the fight against COVID-19 and other pandemics

Contact Info

Product

Resources

About