How hairy are hirsute women?

Barth, Julian H.

doi:10.1046/j.1365-2265.1997.2481062.x

Cited by 16 publications

(9 citation statements)

References 25 publications

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“…Hirsutism is commonly used as an indicator of hyperandrogenism and defined as excessive terminal hair growth in androgen-dependent body areas in women. Although hirsutism was previously reported as the most common skin manifestation, 1,[13][14][15] acne was more common in our report. One previous article reported that South Asian women with PCOS had more severe hirsutism than their Caucasian counterparts, 6 while another study maintained that hirsutism in PCOS patients was more prevalent in Italy and the US than in Japan.…”

Section: Discussioncontrasting

confidence: 55%

Cutaneous manifestations of the subtypes of polycystic ovary syndrome in Korean patients

Hong

Kwon

Park

et al. 2014

Acad Dermatol Venereol

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Section: Discussioncontrasting

confidence: 55%

Cutaneous manifestations of the subtypes of polycystic ovary syndrome in Korean patients

Hong

Kwon

Park

et al. 2014

Acad Dermatol Venereol

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“…Studies of hirsutism often have considerable shortcomings (26,27). This study was designed to record both subjective (F-G score and self-assessment) and objective (plucked hair velocity) measures of response.…”

Section: Discussionmentioning

confidence: 99%

“…However, the subjective scoring systems used to record this exhibit considerable observer variation, even when carried out by the same person (26,27). We addressed this by using a single blinded observer and combined subjective and objective assessments of hair growth.…”

Section: Discussionmentioning

confidence: 99%

The effect of metformin on hirsutism in polycystic ovary syndrome

Kelly

Gordon

2002

Eur J Endocrinol

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Objective: Polycystic ovary syndrome (PCOS) is a common reproductive disorder characterised by insulin resistance and often associated with hirsutism. Insulin sensitising agents, such as metformin, improve both the biochemical and reproductive parameters; however, no study has been designed to specifically assess the effect of metformin on hair growth. Design and patients: Sixteen women with PCOS and hirsutism were enrolled into a 14 month (two 6 month phases with a 2 month washout) double-blind placebo-controlled cross over study. Measurements: Hirsutism was assessed using the Ferriman and Gallwey (F-G) score, patient self-assessment and growth velocity. Weight, height and waist -hip ratio were recorded. Gonadotrophins, androgens, plasma glucose and lipids were also measured. Results: Ten women completed the full 14 month study. There was a significant improvement in hirsutism at the end of the metformin phase compared with placebo: F-G score 15:8^1:4 vs 17:51:2 ðP ¼ 0:025Þ and patient self-assessment 2:4^0:1 vs 3:3^0:3 ðP ¼ 0:014Þ: Growth velocity, in millimetres per day at the end of each phase also improved ð0:67^0:17 vs 0:77^0:11; P ¼ 0:03Þ: There was a non-significant improvement in both sex hormone binding globulin (SHBG) and free androgen index (FAI), although there was a significant difference between baseline and metformin treatment for SHBG ðP ¼ 0:023Þ and FAI ðP ¼ 0:036Þ: Metformin treatment also reduced weight significantly ð91:5^7:6 vs 94:0^9:8 kg; P ¼ 0:009Þ and led to a significant improvement in cycle frequency ð0:53^0:12 vs 0:35^0:08 cycles per month; P ¼ 0:008Þ: Conclusion: We have demonstrated that metformin treatment in a group of women with PCOS results in a clinically and statistically significant improvement in hair growth compared with placebo.

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“…On the other hand, patients who complain of hirsutism with no objective evidence for it provide an example of abnormal illness behaviour in endocrinology, which may cause substantial invalidism. This raises the issue as to whether a woman is hirsute because she thinks she is or because her physician thinks she is (Barth, 1997). Incorporation of patients 0 perceptions and attitudes may be of considerable value in the clinical definition of hirsutism.…”

Section: Hirsutismmentioning

confidence: 99%