How Environmental and Air Pollution Disrupt Spermatogenesis and Male Reproductive Health

Hallak, Jorge; Veras, Mariana Matera; Saldiva, Paulo Hilário Nascimento

doi:10.1016/b978-0-12-801299-4.00001-3

Cited by 6 publications

(3 citation statements)

References 85 publications

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“…Smog pollutants can delay normal conception and in-vitro fertilization (IVF) ( 73 ). The effects of PM 2.5 on the female reproductive system include the dysfunction of ovaries and transportation to the embryo or mutation in the embryo’s DNA ( 74 ). Data from an infertility clinic showed that exposure to PM 2.5 was associated with loss in normal ovarian function resulting in infertility ( 75 ).…”

Section: Endocrine Disrupting Effects Of Particulate Matter (Pm ...mentioning

confidence: 99%

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A comprehensive review on endocrine toxicity of gaseous components and particulate matter in smog

Saleem,

Awan,

Akhtar

2024

Front. Endocrinol.

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Smog is a form of extreme air pollution which comprises of gases such as ozone, sulfur dioxide, nitrogen and carbon oxides, and solid particles including particulate matter (PM2.5 and PM10). Different types of smog include acidic, photochemical, and Polish. Smog and its constituents are hazardaous to human, animals, and plants. Smog leads to plethora of morbidities such as cancer, endocrine disruption, and respiratory and cardiovascular disorders. Smog components alter the activity of various hormones including thyroid, pituitary, gonads and adrenal hormones by altering regulatory genes, oxidation status and the hypothalamus-pituitary axis. Furthermore, these toxicants are responsible for the development of metabolic disorders, teratogenicity, insulin resistance, infertility, and carcinogenicity of endocrine glands. Avoiding fossil fuel, using renewable sources of energy, and limiting gaseous discharge from industries can be helpful to avoid endocrine disruption and other toxicities of smog. This review focuses on the toxic implications of smog and its constituents on endocrine system, their toxicodynamics and preventive measures to avoid hazardous health effects.

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Section: Endocrine Disrupting Effects Of Particulate Matter (Pm ...mentioning

confidence: 99%

“…Similarly, SO 2 is a proven toxicant for the reproductive organs of mammals ( 134 ). Spermatogenesis may consequently improve with a reduction in the level of these toxic oxides ( 74 , 135 ).…”

Section: Cumulative Endocrine Disruptive Effect Of Toxicants In Smogmentioning

confidence: 99%

A comprehensive review on endocrine toxicity of gaseous components and particulate matter in smog

Saleem,

Awan,

Akhtar

2024

Front. Endocrinol.

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“…Infertility is also a worldwide phenomenon as it affects around 15% of couples who seek to obtain a pregnancy, regardless of their cultural and social background after twelve months of unprotected, frequent sexual intercourse [7]. A gradual decrease in sperm quality, particularly sperm count, has been strongly suggested since the 1970s [8][9][10][11]. Although still controversy exists towards methodological standardization of the techniques, environmental factors such as air pollution, habits (tobacco, drugs, toxins, etc.…”

Section: Introductionmentioning

confidence: 99%

Overweight May Have Some Positive Reproductive Benefits as Compared to Obese Represented by Higher Sperm Progressive Motility in Infertile Men

Ciccone

Iori

Milani

et al. 2019

AUN

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Objective: The purpose of this study is to unfold the relationship between overweight, sperm parameters and hormonal levels in infertile men in the reproductive age.Methods: From 2010 to 2013, 76 patients from Androscience, Science and Innovation Center and High-Complexity Andrology Laboratory aged 18 to 55 years were retrospectively analyzed. Semen analysis results were correlated with Body Mass Index (BMI) in patients primarily evaluated for male infertility. According to nutritional status, patients were classified into three major groups, (I) normal range group (18.5 to 24.99 kg/m²), (II) overweight group (25.0 to 29.99 kg/m²) and (III) obesity group (over 30 kg/m²). The relationship between semen quality and hormonal levels was evaluated in each group. Mean results were compared and adopted p>0.05 as statistically significant.Results: Overall, 56% of patients (n=42; mean 36.76 years-old) were classified as overweight, 26% normal BMI (n=20; mean 38.2 y.o.) and 18% (n=14; mean 39.71 y.o.) of the patients were obese. Regarding seminal analysis, no significant difference in sperm concentration, total motility and normal sperm morphology were identified (p>0.05). However, total progressive motility was 14.54% higher in the overweight group in comparison with the obesity group (p=0.063). Conclusion:The results indicated a relationship between overweight infertile men and an increase in progressive motility, further reinforcing the need for a global assessment of men's health, especially in certain subgroups of men such those who desire to father their own offspring currently or in the future.

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Development of a system dynamics model for polycyclic aromatic hydrocarbons and its application to assess the benefits of pollution reduction

Tseng

2018

Ecotoxicology and Environmental Safety

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How Environmental and Air Pollution Disrupt Spermatogenesis and Male Reproductive Health

Cited by 6 publications

References 85 publications

A comprehensive review on endocrine toxicity of gaseous components and particulate matter in smog

A comprehensive review on endocrine toxicity of gaseous components and particulate matter in smog

Overweight May Have Some Positive Reproductive Benefits as Compared to Obese Represented by Higher Sperm Progressive Motility in Infertile Men

Development of a system dynamics model for polycyclic aromatic hydrocarbons and its application to assess the benefits of pollution reduction

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