2000
DOI: 10.1093/neurosurgery/46.1.104
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How Effective Is Endoscopic Third Ventriculostomy in Treating Adult Hydrocephalus Caused by Primary Aqueductal Stenosis?

Abstract: In our experience, the long-term effectiveness of ETVs for adult patients with noncommunicating hydrocephalus was sufficient in only 50% of the cases. One-third of the patients exhibited temporary improvements, lasting 1 to 12 months (average duration, 5 mo) after the ETVs, and then demonstrated deterioration to even worse clinical conditions, despite patent ventriculostomies. All patients who did not exhibit permanent improvements after the ETVs benefited from shunt surgery. Efforts should be made to establis… Show more

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Cited by 86 publications
(42 citation statements)
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“…The long-term success rate would be better evaluated separately for each etiological group [6]. A previous shunt could be a positive predictive factor for ETV success [1], possibly related to the development of secondary aqueductal stenosis [34], although other authors found no differences [35,36] or even worse results [37,38] in shunted patients. ETV could be the first choice in the management of shunt malfunction [39], though a history of shunt infection worsens the success rates [35].…”
Section: Discussionmentioning
confidence: 99%
“…The long-term success rate would be better evaluated separately for each etiological group [6]. A previous shunt could be a positive predictive factor for ETV success [1], possibly related to the development of secondary aqueductal stenosis [34], although other authors found no differences [35,36] or even worse results [37,38] in shunted patients. ETV could be the first choice in the management of shunt malfunction [39], though a history of shunt infection worsens the success rates [35].…”
Section: Discussionmentioning
confidence: 99%
“…7,25 One author found that among 16 adults and adolescents with obstructive hydrocephalus treated with third ventriculostomy, only one required a shunt subsequently at 3.5 years, suggesting that subarachnoid pathways may be normally developed and functioning in late-onset hydrocephalus. 26 Another study evaluating the long-term efficacy of third ventriculostomy for adult patients with hydrocephalus caused by primary aqueductal stenosis found a success rate of 50%. 15 While it has long been accepted that the most successfully treated patients are those with late-onset hydrocephalus, the literature provides evidence to support that this procedure can be successful in primary aqueductal stenosis as well.…”
Section: Indicationsmentioning
confidence: 99%
“…Die wenigen Langzeitstudien zur endoskopischen Ventrikulozisternostomie [7,8,46] besagen, dass die anfänglichen Besserungsraten, die (bei korrekter Indikationsstellung) zwischen 70-100% [6] liegen, nach 5 Jahren auf 50% zurückgehen. Selbst durch eine sehr differenzierte Indikationsstellung [47] gelingt es offensichtlich nicht, diese Rate zu steigern.…”
Section: Erfolgsrate Und "Sudden Death"unclassified
“…Selbst durch eine sehr differenzierte Indikationsstellung [47] gelingt es offensichtlich nicht, diese Rate zu steigern. Betrachtet man in der Längs-schnittanalyse die Wahrscheinlichkeit eines notwendigen Folgeeingriffs, zeigt sich, dass die Versagerquote (und damit die Notwendigkeit eines Zweiteingriffs) beider Verfahren (Shunt und endoskopische Ventrikulozisternostomie) nach 5-7 Jahren gleich hoch ist [5,46,48] und bis zu 50% betragen kann. Dies muss allerdings vor dem Hintergrund gesehen werden, dass sich die Zahlenangaben zur Shunttherapie auf konventionelle Ventile beziehen.…”
Section: Erfolgsrate Und "Sudden Death"unclassified
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