How do transfusion services manage patients taking therapies such as anti‐CD38 and anti‐CD47 known to interfere with red blood cell compatibility testing?
Michael F. Murphy,
Srijana Rajbhandary,
Sharon Carayiannis
et al.
Abstract:BackgroundDrugs such as daratumumab (Darzalex, anti‐CD38) and Hu5F9‐G4 (magrolimab, anti‐CD47) may interfere with red blood cell compatibility testing as CD38 and CD47 are expressed on red blood cells.Study Design and MethodsA survey of AABB member transfusion services was undertaken to understand their experiences of managing patients taking therapeutic monoclonal antibodies that are known to interfere with blood grouping and compatibility testing.ResultsThe survey was distributed to the contact person at US‐… Show more
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