How do people with dementia and family carers value dementia‐specific quality of life states? An explorative “Think Aloud” study

Ratcliffe, Julie; Hutchinson, Claire; Milte, Rachel; Nguyen, Kim‐Huong; Welch, Alyssa; Caporale, Tessa; Corlis, Megan; Comans, Tracy

doi:10.1111/ajag.12646

Cited by 17 publications

(30 citation statements)

References 13 publications

(19 reference statements)

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“…The vast majority of the evaluations present in this review used, as an outcome of the cost-effectiveness of the intervention, quality-adjusted life years, whether alone or combined with other dimensions. QALY is a multidimensional concept whose use is particularly important in chronic conditions, and especially when the results of the intervention affect survival less and the domains of relationships and living more (cognition, mood, behavior, functionality and the ability to live longer without requiring special care or institutionalization), as observed in AD 45 . However, some studies suggest that QALY may not be fully accurate for the evaluation of individuals living with AD, as it is often caregivers, and nonpatients, who provide proxy measures 46 .…”

Section: Discussionmentioning

confidence: 99%

A systematic review of economic evaluations of the use of memantine alone or combined with donepezil for moderate to severe Alzheimer’s disease

Oliveira

Caetano

Steffen

et al. 2019

Rev. bras. geriatr. gerontol.

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Objective: To synthesize the available evidence and state of the art of economic evaluations which evaluate the use of memantine, whether alone or combined with donepezil, for moderate to severe Alzheimer’s disease (AD), focusing on the analytical decision models built. Method: The electronic databases MEDLINE, EMBASE, NHS EED, CEA Registry and LILACS were searched for references. After duplicates were removed, two independent reviewers evaluated the titles and abstracts and subsequently the full texts. The Drummond M. tool was used to evaluate the quality of the studies. Results: After the application of the eligibility criteria, twelve complete economic evaluations were included. One evaluation was a clinical trial, two involved simulations and nine used Markov models. The main outcome measure adopted was dominated by cost per quality adjusted life year (QALY). The use of memantine was considered cost-effective and dominant in eight studies; while in a single study, its use was dominated when compared to donepezil for moderate AD. Sensitivity analyzes were systematically performed, with robust results. The quality assessment indicated that the methodological quality of the studies was good. Conclusion: Although there is some controversy regarding the benefits derived from the use of memantine, whether combined or not with donepezil, the evidence collected suggests that it is cost-effective in the countries where the studies were performed. However, local economic studies need to be performed, given the significant variability derived from the different parameters adopted in the evaluations.

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Section: Discussionmentioning

confidence: 99%

A systematic review of economic evaluations of the use of memantine alone or combined with donepezil for moderate to severe Alzheimer’s disease

Oliveira

Caetano

Steffen

et al. 2019

Rev. bras. geriatr. gerontol.

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“…All eligible participants played the exergame for 30 min on one try-out session. During the exergame performance, the think aloud method ( Ratcliffe et al, 2019 ) was used, and field notes were taken by the observer. After the exergame performance, participants completed the System Usability Scale ( Brooke, 1996 ) and a semi-structured in-depth interview concerning the usability of the device.…”

Section: Methodsmentioning

confidence: 99%

The VITAAL Stepping Exergame Prototype for Older Adults With Major Neurocognitive Disorder: A Usability Study

Swinnen

Bruin

Dumoulin

et al. 2021

Front. Aging Neurosci.

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Purpose: This study investigates the usability of a stepping exergame in older adults with major neurocognitive disorder (MNCD) residing in a long-term care facility.Materials and Methods: A mixed methods study was conducted. Participants played exergames for 30 min on one try-out session. During the exergames, the think aloud method was used, and field notes were taken by the facilitator. Following the exergames, participants completed the System Usability Scale (SUS) and a semi-structured in-depth interview about usability including their personal experiences. Audio files were transcribed and a thematic content analysis of the think aloud data, field notes and interviews were performed using NVivo 12.Results: Twenty-two participants with MNCD were included [mean age = 84.3 ± 5.5 (70–95) years; 81.8% women; Short Physical Performance Battery score = 7.5 ± 3.2 (1–12), Montreal Cognitive Assessment score = 11.9 ± 4.4 (2–19)]. System usability was rated “ok to good” with a mean SUS score of 57.8 (SD = 12.3) with scores ranging from 37.5 to 90.0. Five main themes emerged from the thematic content analysis: (1) perceived user friendliness and acceptability of the exergames; (2) interactional experience; (3) motivational factors; (4) training modalities; and (5) risks. There were no adverse events nor dropouts.Conclusion: Participants evaluated the usability of the exergames positively. The results indicate that the stepping exergame is usable in older adults with MNCD.

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“…Ratcliffe et al provide evidence on the application of a qualitative thinkaloud methodology to actively engage people with dementia and their carers in valuing particular quality‐of‐life states. People with dementia and carers used a range of decision‐making strategies, thereby facilitating assessment of the benefits of dementia care services and supports for economic evaluation from their own perspective.…”

mentioning

confidence: 99%

Organising care, practice and participative research: Papers from the cognitive decline partnership centre

2019

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How do people with dementia and family carers value dementia‐specific quality of life states? An explorative “Think Aloud” study

Cited by 17 publications

References 13 publications

A systematic review of economic evaluations of the use of memantine alone or combined with donepezil for moderate to severe Alzheimer’s disease

A systematic review of economic evaluations of the use of memantine alone or combined with donepezil for moderate to severe Alzheimer’s disease

The VITAAL Stepping Exergame Prototype for Older Adults With Major Neurocognitive Disorder: A Usability Study

Organising care, practice and participative research: Papers from the cognitive decline partnership centre

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