How Dietary Deficiency Studies Have Illuminated the Many Roles of Vitamin A During Development and Postnatal Life

Asson-Batres, Mary Ann

doi:10.1007/978-3-030-42282-0_1

Cited by 3 publications

(4 citation statements)

References 112 publications

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“…The optimal supply of this substance ensures the proper activity of the immune system and strengthens both humoral and cellular components. Vitamin A is responsible for the appropriate functioning of the mucous membranes of the eyeball, digestive, respiratory and genitourinary systems and the course of the IgA-dependent response [62][63][64]. According to some research, vitamin A is one of the most effective substances in delaying ageing.…”

Section: Vitamin Amentioning

confidence: 99%

“…Vitamin A also protects the resulting collagen against degeneration by stimulating the reconstruction of reticulin fibres and the formation of new blood vessels in the papillary layer of the dermis. It has a significant impact on the water-fat balance, thus reducing the roughness and peeling of the skin [62][63][64].…”

Section: Vitamin Amentioning

confidence: 99%

“…The application of vitamin A in treating acne, wrinkles, lichenoid changes, emphysema, hyperthyroidism, abscesses, boils and open ulcers is widely recognised. Moreover, vitamin A is essential for developing bones, teeth and proper functioning of the genital organs [62][63][64].…”

Section: Vitamin Amentioning

confidence: 99%

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Reasonableness of Enriching Cow’s Milk with Vitamins and Minerals

Woźniak

Cichy

Dobrzyńska

et al. 2022

Foods

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Milk is an exceptional nutritional product that has been used for many millennia in human nutrition. Milk is a source of many valuable nutrients, including calcium, vitamin B, an especially significant amount of vitamin B2 and fat-soluble vitamins, such as A, D and E. Milk is an attractive product for fortification as it has a high nutritional density in a small volume and a relatively low price. Research shows positive health effects of drinking milk and consuming dairy products. Even more health benefits can be obtained from consuming fortified dairy products. A literature review, current nutritional recommendations, medical recommendations and an analysis of the market situation all recommend introducing milk enriched with minerals in combination with vitamins to the market. This concept corresponds to the current market demand and may supplement the missing and expected range of fortified milk and the correct number of recipients.

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Section: Vitamin Amentioning

confidence: 99%

Section: Vitamin Amentioning

confidence: 99%

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Reasonableness of Enriching Cow’s Milk with Vitamins and Minerals

Woźniak

Cichy

Dobrzyńska

et al. 2022

Foods

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“…However, both THs and RA of maternal origin mediate very early developmental events. The maternal-fetal exchange of these factors begins though the transient structure yolk sac and the fetal exocoelomic cavity [ 12 , 13 , 14 ], after which the presence of different classes of TH membrane transporters in the placenta, such as organic anion transporting polypeptides, monocarboxylate transporters, and transthyretin for THs, together with the placental TH inactivating enzyme deiodinase 3 (D3), guarantee- the feto-maternal TH equilibrium [ 15 ]. The role of placental retinoic binding proteins (RBPs), transthyretin and other proteins (Strat6, CRBPI) as vitamin A trans-placental carriers is still debated [ 10 ].…”

Section: Introductionmentioning

confidence: 99%

Thyroid Hormone Signaling in Embryonic Stem Cells: Crosstalk with the Retinoic Acid Pathway

Fernández

Pannella

Baldassarro

et al. 2020

IJMS

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While the role of thyroid hormones (THs) during fetal and postnatal life is well-established, their role at preimplantation and during blastocyst development remains unclear. In this study, we used an embryonic stem cell line isolated from rat (RESC) to study the effects of THs and retinoic acid (RA) on early embryonic development during the pre-implantation stage. The results showed that THs play an important role in the differentiation/maturation processes of cells obtained from embryoid bodies (EB), with thyroid hormone nuclear receptors (TR) (TRα and TRβ), metabolic enzymes (deiodinases 1, 2, 3) and membrane transporters (Monocarboxylate transporters -MCT- 8 and 10) being expressed throughout in vitro differentiation until the Embryoid body (EB) stage. Moreover, thyroid hormone receptor antagonist TR (1-850) impaired RA-induced neuroectodermal lineage specification. This effect was significantly higher when cells were treated with retinoic acid (RA) to induce neuroectodermal lineage, studied through the gene and protein expression of nestin, an undifferentiated progenitor marker from the neuroectoderm lineage, as established by nestin mRNA and protein regulation. These results demonstrate the contribution of the two nuclear receptors, TR and RA, to the process of neuroectoderm maturation of the in vitro model embryonic stem cells obtained from rat.

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Serum Vitamin A Levels as a Novel Predictor for Respiratory Distress Syndrome in Neonates: Is It Beneficial?

Elfarargy

Abu-Risha

Al-Ashmawy

et al. 2022

EMIDDT

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Background: Neonatal respiratory distress syndrome (RDS) is a very important dangerous disease in neonates and is accompanied by neonatal complications and death. Patients and Methods: A case-control study, with the identification number TCTR20210206001 was done on 100 neonates who were admitted to the neonatal intensive care unit (NICU) of Tanta University Hospital (TUH) suffering from RDS (patient group) and 100 healthy neonates (control group). Estimation of serum vitamin A (retinol) was occurred for all neonates of this study within the first four hours after birth before any nutrition or therapies. Results: Showed no significant difference between serums retinol (RT) levels in grade 1&2 RDS neonates (patient group) and the serum RT levels in the control group while there was significant difference between serums retinol levels in grade 3&4 RDS neonates (patient group) and the serum retinol levels in the control group where the P-value was 0.006, 0.002 respectively. Conclusion : Serum vitamin A levels in neonates were decreased in RDS neonates and could be used as a predictor for the development and severity of RDS. Recommendation: Routine estimation of serum vitamin A levels in neonates as a novel predictor for neonatal RDS.

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How Dietary Deficiency Studies Have Illuminated the Many Roles of Vitamin A During Development and Postnatal Life

Cited by 3 publications

References 112 publications

Reasonableness of Enriching Cow’s Milk with Vitamins and Minerals

Reasonableness of Enriching Cow’s Milk with Vitamins and Minerals

Thyroid Hormone Signaling in Embryonic Stem Cells: Crosstalk with the Retinoic Acid Pathway

Serum Vitamin A Levels as a Novel Predictor for Respiratory Distress Syndrome in Neonates: Is It Beneficial?

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