How Did We Get Here?: A Historical Review and Critical Analysis of Anticoagulation Therapy Following Mechanical Valve Replacement

Macisaac, S.; Jaffer, Iqbal H.; Belley‐Côté, Emilie P.; McClure, Ghyslaine; Eikelboom, John W.; Whitlock, Richard

doi:10.1161/circulationaha.119.041105

Cited by 18 publications

(15 citation statements)

References 61 publications

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“…Advances in society have led people to care more about quality of life than length of life. In addition to considering the performance of the two prosthetic valves, the postoperative short-term and longterm complications, the survival of patients and the recurrence of the disease, quality of life has also become an important evaluation criterion in choosing the type of prosthetic valve [14,15]. This study retrospectively analyzed the quality of life and postoperative anxiety of sexagenarian patients who underwent biological or mechanical aortic valve replacement in our center to provide some reference factors for valve selection for sexagenarian patients to be used in the future.…”

Section: Discussionmentioning

confidence: 99%

Quality of life in sexagenarians after aortic biological vs mechanical valve replacement: a single-center study in China

Wang

Huang

et al. 2020

J Cardiothorac Surg

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Objective: This article aimed to study the quality of life and anxiety of sexagenarian patients who underwent aortic biological vs mechanical valve replacement in a single center in China. Methods: The clinical data of 78 patients aged 60 to 70 years who underwent aortic prosthetic valve replacement were retrospectively analyzed in our hospital from June 2017 to February 2018. Patients were divided into two groups depending on the type of prosthetic valve they received (biological valve group vs mechanical valve group). The SF-36 was completed by all patients at discharge and at one-year follow-up, and the cardiac anxiety questionnaire (CAQ) was also completed at one-year follow-up. Results: There was no statistically significant difference between the two groups in general clinical data or SF-36 score at discharge. However, at one-year follow-up, the SF-36 scores were significantly higher in the biological valve group than in the mechanical valve group, and the CAQ scores in fear and anxiety, avoidance and attention in the mechanical valve group were significantly higher than those in the biological valve group. Conclusions: Based on the postoperative quality of life and anxiety scores of sexagenarian patients who underwent biological vs mechanical valve replacement in this study, a biological valve has more value than a mechanical valve for sexagenarians undergoing aortic valve replacement.

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Section: Discussionmentioning

confidence: 99%

Quality of life in sexagenarians after aortic biological vs mechanical valve replacement: a single-center study in China

Wang

Huang

et al. 2020

J Cardiothorac Surg

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“…Table 1 lists recommended INR targets for patients with mechanical heart valves. European, US, and NICE recommendations vary, indicating areas of continuing uncertainty, and likely reflecting a lack of high quality evidence 1112. Gradually increase the monitoring interval to weekly, fortnightly, and monthly if INR is stable.…”

Section: How Is Warfarin Given and Monitored?mentioning

confidence: 99%

Warfarin in patients with mechanical heart valves

Catterall

Isles

2020

BMJ

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“…Currently, new anticoagulation drugs are gradually introduced in the clinic, but the efficacy of the best anticoagulation treatment is uncertain, and the choice of anticoagulation schemes is ambiguous. Choosing the optimal anticoagulation schedule requires comprehensive consideration of the patient's overall cognition, values, disease treatment, and factors such as preference and disease condition [ 3 , 4 ]. The type of anticoagulation therapy has an important impact on the effects of anticoagulants, and when Posed with the risk of bleeding and thrombosis, patients often experience conflicts in decision-making [ 5 , 6 ].…”

Section: Introductionmentioning

confidence: 99%

Qualitative study of willingness and demand for participation in decision-making regarding anticoagulation therapy in patient undergoing heart valve replacement

Zang

Liu

Chen

2022

BMC Med Inform Decis Mak

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Background Promoting patient participation in decision-making aims to maintain the partnership between doctors and patients, reflect the patients’ goals, values, and preferences, and achieve patient-centered care. Realizing patient-centered care, shared collaboration between doctors and patients, and the decision-making process that considers the patients’ priorities and goals are the keys to high-quality health care. Therefore, it is indispensable to analyze the patients’ willingness to participate in the decision-making process and related participation needs regarding anticoagulation treatment for patients undergoing valve replacement. Purpose To analyze the patients’ willingness to participate in the decision-making process and the participation needs of patients undergoing mechanical cardiac valve replacement in the process of anticoagulation therapy to provide a basis for promoting patients' participation in decision-making. Methods Using phenomenological research methods, data were collected through semistructured interviews. Patients were interviewed after mechanical valve replacement from June to August 2021 in a Grade A hospital in Nanjing. Data were analyzed according to the Colaizzi phenomenology method. Results Three major themes were identified from the data: strong willingness to participate but low actual participation, supportive needs, and family members’ participation. Conclusions This study guided interventions to encourage patients who underwent heart valve replacement to participate in the decision-making process. From the patient's perspective, obtaining support in the decision-making process and caregiver enthusiasm is important. This study prompted thoughts about the use of auxiliary tools and provided a reliable basis for constructing decision-making auxiliary programs to guide clinical practice.

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How Did We Get Here?: A Historical Review and Critical Analysis of Anticoagulation Therapy Following Mechanical Valve Replacement

Cited by 18 publications

References 61 publications

Quality of life in sexagenarians after aortic biological vs mechanical valve replacement: a single-center study in China

Quality of life in sexagenarians after aortic biological vs mechanical valve replacement: a single-center study in China

Warfarin in patients with mechanical heart valves

Qualitative study of willingness and demand for participation in decision-making regarding anticoagulation therapy in patient undergoing heart valve replacement

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