How cortico-basal ganglia-thalamic subnetworks can shift decision policies to maximize reward rate
Jyotika Bahuguna,
Timothy Verstynen,
Jonathan E. Rubin
Abstract:All mammals exhibit flexible decision policies that depend, at least in part, on the cortico-basal ganglia-thalamic (CBGT) pathways. Yet understanding how the complex connectivity, dynamics, and plasticity of CBGT circuits translates into experience-dependent shifts of decision policies represents a longstanding challenge in neuroscience. Here we used a computational approach to address this problem. Specifically, we simulated decisions driven by CBGT circuits under baseline, unrewarded conditions using a spik… Show more
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