How closely do blood gas electrolytes and haemoglobin agree with serum values in adult emergency department patients: An observational study

Gibbons, Michael; Klim, Sharon; Mantzaris, A.; Dillon, Oliver; Kelly, Anne‐Maree

doi:10.1111/1742-6723.13133

Cited by 9 publications

(25 citation statements)

References 9 publications

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“…88 A retrospective study and prospective analytical observational studies at multiple health care sites showed sufficient agreement between sodium, potassium, and ionized calcium results obtained from blood gas and central laboratory analyzers to enable prompt clinical decision-making. [89][90][91] With proper training and education of the ED care team, POCT can be used as an effective tool for managing patient flow in the ED. 92 C-reactive protein (CRP) provides diagnostic value for ruling in or ruling out serious bacterial infection in febrile children.…”

Section: Clinical Chemistrymentioning

confidence: 99%

Current Status of Clinical Application of Point-of-Care Testing

Park

2020

Archives of Pathology &Amp; Laboratory Medicine

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Context.— The clinical applications of point-of-care testing (POCT) are gradually increasing in many health care systems. Recently, POCT devices using molecular genetic method techniques have been developed. We need to examine clinical pathways to see where POCT can be applied to improve them. Objective.— To introduce up-to-date POCT items and equipment and to provide the content that should be prepared for clinical application of POCT. Data Sources.— Literature review based on PubMed searches containing the terms point-of-care testing, clinical chemistry, diagnostic hematology, and clinical microbiology. Conclusions.— If medical resources are limited, POCT can help clinicians make quick medical decisions. As POCT technology improves and menus expand, areas where POCT can be applied will also increase. We need to understand the limitations of POCTs so that they can be optimally used to improve patient management.

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Section: Clinical Chemistrymentioning

confidence: 99%

Current Status of Clinical Application of Point-of-Care Testing

Park

2020

Archives of Pathology &Amp; Laboratory Medicine

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“…For patients with a severe or life-threatening degree of the illness, the blood gas analyzer (BGA) is usually used clinically to achieve rapid detection. The BGA uses direct ISE for direct analysis without the need to first dilute the sample, and the results can be obtained within 1 to 5 min [6][7][8][9][10]. The BGA can be divided into two types: benchtop and portable.…”

Section: Introductionmentioning

confidence: 99%

Electrochemical Detection of Electrolytes Using a Solid-State Ion-Selective Electrode of Single-Piece Type Membrane

Chen

Wang

2021

Biosensors

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This study aimed to develop simple electrochemical electrodes for the fast detection of chloride, sodium and potassium ions in human serum. A flat thin-film gold electrode was used as the detection electrode for chloride ions; a single-piece type membrane based solid-state ion-selective electrode (ISE), which was formed by covering a flat thin-film gold electrode with a mixture of 7,7,8,8-tetracyanoquinodimethane (TCNQ) and ion-selective membrane (ISM), was developed for sodium and potassium ions detection. Through cyclic voltammetry (CV) and square-wave voltammetry (SWV), the detection data can be obtained within two minutes. The linear detection ranges in the standard samples of chloride, sodium, and potassium ions were 25–200 mM, 50–200 mM, and 2–10 mM, with the average relative standard deviation (RSD) of 0.79%, 1.65%, and 0.47% and the average recovery rates of 101%, 100% and 96%, respectively. Interference experiments with Na+, K+, Cl−, Ca2+, and Mg2+ ions demonstrated that the proposed detection electrodes have good selectivity. Moreover, the proposed detection electrodes have characteristics such as the ability to be prepared under relatively simple process conditions, excellent detection sensitivity, and low RSD, and the detection linear range is suitable for the Cl−, Na+ and K+ concentrations in human serum.

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“…5,6 Despite these advantages, the results obtained by a POCT system are not always interchangeable with those obtained by traditional core laboratory instrumentation. 5,7,8 Moreover, inappropriate test use leads to unnecessary increases in cost of care and can undermine patient management. 2,7 Therefore, the utility of any POCT system must be evaluated for each patient and clinical environment before its implementation in clinical practice.…”

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confidence: 99%

“…2,7 Therefore, the utility of any POCT system must be evaluated for each patient and clinical environment before its implementation in clinical practice. 1,4,7,8 Acid-base disturbances are characteristically common in nephrology departments. These imbalances can have either metabolic or respiratory origins, and can be compensated or not.…”

mentioning

confidence: 99%

“…Publications regarding POCT BGA are scarce, mostly limited to emergency and pulmonology settings. [2][3][4]7,8,11,12 Publications available about POCT methods aimed at nephrologic patients are mostly for diagnosis and do not include BGA. [13][14][15][16] To the best of our knowledge, the present study assesses clinical, operative, and economic outcomes of POCT BGA in a nephrology department for the first time.…”

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confidence: 99%

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Clinical, Operative, and Economic Outcomes of the Point-of-Care Blood Gases in the Nephrology Department of a Third-Level Hospital

Moreno

Sáez

Calle

et al. 2020

Archives of Pathology &Amp; Laboratory Medicine

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Context.— Point-of-care testing allows rapid analysis and short turnaround times. To the best of our knowledge, the present study assesses, for the first time, clinical, operative, and economic outcomes of point-of-care blood gas analysis in a nephrology department. Objective.— To evaluate the impact after implementing blood gas analysis in the nephrology department, considering clinical (differences in blood gas analysis results, critical results), operative (turnaround time, elapsed time between consecutive blood gas analysis, preanalytical errors), and economic (total cost per process) outcomes. Design.— A total amount of 3195 venous blood gas analyses from 688 patients of the nephrology department before and after point-of-care blood gas analyzer installation were included. Blood gas analysis results obtained by ABL90 FLEX PLUS were acquired from the laboratory information system. Statistical analyses were performed using SAS 9.3 software. Results.— During the point-of-care testing period, there was an increase in blood glucose levels and a decrease in pCO2, lactate, and sodium as well as fewer critical values (especially glucose and lactate). The turnaround time and the mean elapsed time were shorter. By the beginning of this period, the number of preanalytical errors increased; however, no statistically significant differences were found during year-long monitoring. Although there was an increase in the total number of blood gas analysis requests, the total cost per process decreased. Conclusions.— The implementation of a point-of-care blood gas analysis in a nephrology department have a positive impact on clinical, operative, and economic terms of patient care.

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How closely do blood gas electrolytes and haemoglobin agree with serum values in adult emergency department patients: An observational study

Abstract: Agreement between blood gas analysis and laboratory analysis for sodium, potassium and haemoglobin concentrations shows acceptable agreement for use in time critical clinical decision-making in ED.

Cited by 9 publications

References 9 publications

Current Status of Clinical Application of Point-of-Care Testing

Current Status of Clinical Application of Point-of-Care Testing

Electrochemical Detection of Electrolytes Using a Solid-State Ion-Selective Electrode of Single-Piece Type Membrane

Clinical, Operative, and Economic Outcomes of the Point-of-Care Blood Gases in the Nephrology Department of a Third-Level Hospital

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