How Can Selected Dietary Ingredients Influence the Development and Progression of Endometriosis?

Abstract

Endometriosis is a chronic, hormone-dependent disease characterized by the presence of endometrial tissue in ectopic locations. Since the treatment options for this disease are still limited, and the cure rate is unsatisfactory, the search for ways to treat symptoms and modify the course of the disease is of key importance in improving the quality of life of patients with endometriosis. So far, the literature has shown that nutrition can influence endometriosis through hormonal modification and altering the inflammatory or oxidative response. Since the importance of nutrition in this disease is still a subject of scientific research, we aimed to summarize the current knowledge on the role of dietary modifications in endometriosis. Our review showed that nutrients with anti-inflammatory and antioxidant properties, including most vitamins and several trace elements, may influence the pathogenesis of endometriosis and can be considered as the nutrients preventing the development of endometriosis. However, despite the many discoveries described in this review, further interdisciplinary research on this topic seems to be extremely important, as in the future, it may result in the development of personalized therapies supporting the treatment of endometriosis.

Association Between the Oxidative Balance Score and Endometriosis: A Population-Based Study

“…Irregular menstruation belongs to an inflammatory event, 32 and use of female hormones may also facilitate the occurrence of endometriosis, which is a hormone-dependent disease. 33 These populations should pay attention to menstruation management and female hormone use. Keeping balanced oxidative status in dietary intake and lifestyle might reduce the odds of endometriosis through monitoring the OBS.…”

Oxidative Imbalance in Endometriosis-Related Infertility—The Therapeutic Role of Antioxidants

“…To date, there is no single appropriate management method for the treatment of endometriosis-associated infertility, and both surgery and assisted reproductive techniques (ARTs) could be offered [ 13 , 14 ]. Overall, a great amount of scientific evidence suggests the efficacy of some supportive therapies, including a proper diet, supplementation, and physical activity, in endometriosis management [ 15 , 16 ]. Since supplementation particularly concerns products that can modulate the processes underlying the disease, such as inflammation or oxidative stress (OS), it seems crucial to supplement products with antioxidant potential [ 17 ].…”