How calorie restriction slows aging: an epigenetic perspective

Rejuvenation of young blood on aging organs: Effects, circulating factors, and mechanisms

“…Scientists have dedicated extensive efforts to researching various interventions aimed at mitigating the effects of aging. Some methods that have shown promising results in animal models include stem cell transplantation [ 2 ], exercise [ 3 ], and calorie restriction [ 4 ]. However, the translation of these approaches from animals to humans poses practical and unresolved challenges, demanding perseverance in the long run.…”

“…Considering the limitations of the aforementioned methods [ [2] , [3] , [4] ], an important solution is to investigate the disparities between the elderly and the young, and determine whether addressing these deficiencies could delay the aging process. This approach potentially offers wider applicability and safety.…”