How and Why Are Irritability and Depression Linked?

Vidal‐Ribas, Pablo; Stringaris, Argyris

doi:10.1016/j.chc.2020.10.009

Cited by 29 publications

(19 citation statements)

References 84 publications

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“…Second, our female subsample reported higher depressive symptoms than men and we found that measures of irritability and depression correlated highly in our sample. A significant body of the literature links irritability with depression ( Fava et al, 2010 ; Jha et al, 2020; Judd et al, 2013 ; Pedrelli et al, 2015; Stringaris et al, 2009 ; Vidal-Ribas et al, 2016 ; Vidal-Ribas & Stringaris, 2021 ), and evidence showed that in a large cohort of MDD patients, irritability was more common among female and younger participants ( Perlis et al, 2009 ). Taken together, these variables (i.e., age, professional status, and depressive symptoms) might account for the emergence of a gender bias in our study.…”

Section: Discussionmentioning

confidence: 99%

French Adaptation of the Brief Irritability Test: Factor Structure, Psychometric Properties, and Relationship with Depressive Symptoms

Bellaert

Blekić

Arachchige

et al. 2022

Psychologica Belgica

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The Brief Irritability Test (BITe, Holtzman et al., 2014 ) is a brief, reliable, and valid self-report measure of irritability. Despite the growing interest to understand the underlying causes and consequences of irritability, this questionnaire has not been developed and validated for a French-speaking population yet. In the present study, 413 participants completed our French adaptation of the BITe (i.e., TCI; Test Court d’Irritabilité) and measures of associated constructs (depression, anger, hostility, and aggression) and well-being (life satisfaction and social support). Descriptive, psychometric (i.e., Cronbach alpha and Spearman correlation coefficients), and factor analyses were conducted. An exploratory factor analysis in sample 1 (n = 209), yielded one single factor. The confirmatory factor analysis in sample 2 (n = 204) showed a reasonable fit of this single factor model explaining 55.5% of the variance and presenting a strong internal consistency (α = .80). Compared to the original English questionnaire, the TCI shares similar unidimensional factor organization and correlations with other constructs, although a gender bias was identified, with women scoring higher than men. Irritability was higher among respondents in the age range 17–25, compared to older adults. A hierarchical regression analysis showed that TCI scores significantly predict depressive symptoms when demographics were controlled for. In summary, the TCI presents good psychometric properties and could constitute a valuable tool to evaluate irritability in clinical and research contexts.

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Section: Discussionmentioning

confidence: 99%

French Adaptation of the Brief Irritability Test: Factor Structure, Psychometric Properties, and Relationship with Depressive Symptoms

Bellaert

Blekić

Arachchige

et al. 2022

Psychologica Belgica

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“…At least 50% of major depressive disorder patients show irritability during the depressive episode ( 81 ), and irritability predicts a greater severity of major depressive disorder ( 82 ). Shared risk factors, including genetic risk, common temperamental characteristics and negative parenting styles, are used to explain the association between irritability and depression ( 83 , 84 ). Similarly, concentration difficulties are common in anxiety disorders ( 85 ), and previous experimental evidence has confirmed the detrimental influence of anxiety on concentration ( 86 ).…”

Section: Discussionmentioning

confidence: 99%

Network analysis of anxiety and depression in the functionally impaired elderly

Yang

Guo

Cao

et al. 2022

Front. Public Health

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BackgroundEvidence from previous studies has confirmed that functionally impaired elderly individuals are susceptible to comorbid anxiety and depression. Network theory holds that the comorbidity emerges from interactions between anxiety and depression symptoms. This study aimed to investigate the fine-grained relationships among anxiety and depression symptoms in the functionally impaired elderly and identify central and bridge symptoms to provide potential targets for intervention of these two comorbid disorders.MethodsA total of 325 functionally impaired elderly individuals from five communities in Xi'an, China, were recruited for our investigation. The GAD-7 and PHQ-9 were used to measure anxiety and depression, respectively. SPSS 22.0 software was used for descriptive statistics, and R 4.1.1 software was used for network model construction, expected influence (EI) evaluation and bridge expected influence (BEI) evaluation.ResultsIn the network, there were 35 edges (indicating partial correlations between symptoms) across the communities of anxiety and depression, among which the strongest edge was A1 “Nervousness or anxiety”-D2 “Depressed or sad mood.” A2 “Uncontrollable worry” and D2 “Depressed or sad mood” had the highest EI values in the network, while A6 “Irritable” and D7 “Concentration difficulties” had the highest BEI values of their respective community. In the flow network, the strongest direct edge of D9 “Thoughts of death” was with D6 “Feeling of worthlessness.”ConclusionComplex fine-grained relationships exist between anxiety and depression in functionally impaired elderly individuals. “Uncontrollable worry,” “depressed or sad mood,” “irritable” and “concentration difficulties” are identified as the potential targets for intervention of anxiety and depression. Our study emphasizes the necessity of suicide prevention for functionally impaired elderly individuals, and the symptom “feeling of worthlessness” can be used as an effective target.

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“…5 Nüfus temelli çalışmalarda, çocuklarda kronik sinirliliğin ebeveynlerdeki depresyon ve anksiyete ile ilişkisi olduğunu saptamıştır. [6][7][8][9] Öfke patlamaları ve irritabilite gibi YDDB semptomları, MDB olan ebeveynlerin çocuklarında en sık görülen semptomlar arasındadır. 10 Ebeveynlerinde depresyon öyküsü olan çocukların irritabilite açısından risk teşkil ettiği bildirilmektedir.…”

Section: Introductionunclassified

“…10 Ebeveynlerinde depresyon öyküsü olan çocukların irritabilite açısından risk teşkil ettiği bildirilmektedir. 8 13 tarafından yapılmıştır.…”

Section: Introductionunclassified

Psychopathologies in children whose parents are diagnosed with a major depressive disorder or anxiety disorder

Bozduman

Aksu

Toros

2021

Mersin Üniversitesi Sağlık Bilimleri Dergisi

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Amaç: Majör depresif bozukluk (MDB) veya anksiyete bozukluğu (AB) tanılı ebeveynlerin çocuklarında yıkıcı duygudurum düzenleyememe bozukluğu (YDDB) başta olmak üzere ruhsal bozuklukların araştırılması amaçlanmıştır. Yöntem: Mersin Üniversitesi Tıp Fakültesi Psikiyatri polikliniğine Eylül 2018-Eylül 2019 tarihleri arasında başvuran MDB olan 46 ve AB olan 34 ebeveynin 6-18 yaşları arasındaki 80 çocuğu çalışmaya dâhil edilmiştir. Kontrol grubunu, herhangi bir psikiyatrik rahatsızlığı olmayan Mersin Üniversitesi Tıp Fakültesi pediatri polikliniğine basit fiziksel yakınmalar ile başvuran sağlıklı ebeveynlerin aynı yaştaki 40 sağlıklı çocuğu oluşturmaktadır. Çocuk ve ebeveyn ile Okul Çağı (6-18 Yaş) Çocukları İçin Duygulanım Bozuklukları ve Şizofreni Görüşme Çizelgesi-Şimdi ve Yaşam Boyu Versiyonu Türkçe (ÇGDŞ-ŞY-T), Beck depresyon, Beck anksiyete, DSM-IV'e dayalı DEHB tanı ve değerlendirme ölçeği, Çocukluk Çağı Kaygı Bozuklukları Ölçeği (ÇATÖ), Çocuklar için Depresyon Ölçeği (ÇDÖ) uygulanmıştır. Bulgular: Çalışmamızda ebeveyninde AB ve MDB olan çocuklarda daha fazla ruhsal bozukluk saptandı. En sık görülen psikopatoloji DEHB iken bunu YAB, MDB, sosyal fobinin takip ettiği görüldü. Tüm örneklemde DSM-5'e göre sadece bir olgu (%2.9) YDDB tanısını karşıladı. Hem MDB hem AB grubunda karşıt olma karşı gelme puanları (p=0.019), AB grubunda ise davranım bozukluğu puanları (p=0.043) kontrollerden anlamlı düzeyde yüksekti. Sonuç: Ebeveynlerinde ruhsal bozukluk olan çocuklar psikopatoloji gelişimi açısından risk altındadır ve ebeveynlere yönelik uygun tarama programlarının geliştirilmesi önem arz etmektedir. Çocuk psikiyatri kliniklerine en sık başvuru şikâyetleri sinirlilik, öfke patlamaları gibi YDDB semptomları iken çalışma sonuçları tanısal anlamda YDDB'nin düşük olduğunu göstermiştir. Bu durum ileri çalışmalarda daha çok YDDB'nin semptomlar düzeyinde irdelenmesinin faydalı olabileceğini düşündürmektedir.

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How and Why Are Irritability and Depression Linked?

Cited by 29 publications

References 84 publications

French Adaptation of the Brief Irritability Test: Factor Structure, Psychometric Properties, and Relationship with Depressive Symptoms

French Adaptation of the Brief Irritability Test: Factor Structure, Psychometric Properties, and Relationship with Depressive Symptoms

Network analysis of anxiety and depression in the functionally impaired elderly

Psychopathologies in children whose parents are diagnosed with a major depressive disorder or anxiety disorder

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