In this scientific work, the basic synergetic principles of the development of the paradigm of civilizations are substantiated, an assessment of the time boundaries within which civilizations exist, the features of their own path of development of Uzbek culture are revealed. It is especially drawn attention to the sociocultural codes of civilization, a combination of which identifies the essence of Uzbek civilization. However, gives the reasons for the threat of the existence of civilizations and the prospects for their further development. The problem of the paradigm of civilizations interested many inquisitive minds of mankind, philosophical schools and trends. Its origins can be found in antiquity and in the Middle Ages. Dosocrats, Plato, Aristotle, Stoics, Epicureans, Neoplatonists, Thomas Aquinas, al-Farabi, Ibn Sina developed problems of society and history within the framework of the classical metaphysical and dialectical-idealistic tradition. It is believed that the modern form and meaning of the term civilization in some cases preserves what was put into circulation, first of all, by the French and English enlighteners in the second half of the 18th century, who proposed a universal scheme for the development of mankind-savagery, barbarism, civilization and focused on the search for the source of the development of society, the driving forces of history: V. Voltaire, J. Kondors, A. Turgot. This problem has not been developed in Uzbekistan from a philosophical point of view, in particular, that part of it that deals with ontological and epistemological aspects. In connection with the study, dialectical, formal-logical, historical-morphological methods were used, as well as comparative analysis methods.