An enduring legacy from the heyday of Mendelian genetics is talk of 'genes for'. Such talk suggests straightforwardly that genes make characters. But for over a century, thoughtful biologists have insisted such an understanding is mistaken. For them, a gene is a chromosomal difference that, when internal and external environments are otherwise equal, makes a phenotypic difference; 'genes for' talk is but shorthand for this more complex understanding. This paper examines the remarkable durability of the disowned, deterministic character-making understanding, placing particular emphasis on the role of the traditional, start-with-Mendel curriculum in investing that understanding with a heuristic power which later teaching may never fully displace. The paper also reports on recent experimental work exploring the potential of a reordered curriculum for teaching genetics without bolstering genetic determinism.Evelyn Fox Keller's The century of the gene (2000) is the most famous obituary of the entity forever associated with Gregor Mendel (Keller 2000). But what kind of a life did the Mendelian gene ever really have, anyway? Haven't thoughtful biologists long regarded the idea of it as an oversimplification? Indeed, from early days, all kinds of complexity have been allowed for. At the same time, the power of Mendelian explanations to cut through complexity and expose underlying simplicity has been relentlessly showcased. In the spirit of Keller's subsequent book, Making sense of life (2002), I want in what follows both to exhibit this 'ambi-valence' (Keller 2002, 130) and to suggest how crucial it has been in making the Mendelian geneand the determinism it underwritesso long-lived. Although my analysisof what has made gene talk so durable will not coincide with hers, our accounts are complementary, to such an extent that that the curriculum reform experiment I shall describe at the end could well be considered applied Kellerism.
The Mendelian geneGene concepts are legion. 1 By 'the Mendelian gene,' I mean the entity that does the explaining in elementary genetics, e.g., in explaining why two blue-eyed parents can have only blue-eyed children. On the standard Mendelian explanation, there is a gene for eye colour, and it comes in two versions or 'alleles.' There is the brown-eye allele, which is dominant. And there is the blue-eye allele, which is recessive. The father's sperm and the mother's egg each carry only one allele. If the zygote formed from the union of these gametes brings together a brown-eye allele with another brown-eye allele, then the child will have brown eyes. If the zygote brings together a brown-eye allele and a blue-eye allele, then the child will also have brown eyes, because brown-eye is dominant. Only if the zygote brings together a blue-eye allele with another blue-eye allele will the child have blue eyes. A corollary is that, since blue-eyed parents can only ever contribute blue-eye alleles, two blueeyed parents will have only blue-eyed children.Note two features of the entity invoked in this ex...