House dust mite-specific immunotherapy and tropomyosin sensitizations: harm or benefit for patients?

Pevec, Branko; Pevec, Mira Radulović; Marković, Asja Stipić; Batišta, Irena

doi:10.1186/2045-7022-3-s3-p44

Cited by 2 publications

(2 citation statements)

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“…The correlation between shellfish and dust mites suggests the possibility that AIT for dust mites may lead to the improvement of shellfish allergy [ 155 , 156 ]. On the other hand, cases have been reported of shrimp allergy following mite-specific immunotherapy [ 157 , 158 , 159 ].…”

Section: Managementmentioning

confidence: 99%

IgE Mediated Shellfish Allergy in Children—A Review

et al. 2023

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Shellfish is a leading cause of food allergy and anaphylaxis worldwide. Recent advances in molecular characterization have led to a better understanding of the allergen profile. High sequence homology between shellfish species and between shellfish and house dust mites leads to a high serological cross-reactivity, which does not accurately correlate with clinical cross-reactions. Clinical manifestations are immediate and the predominance of perioral symptoms is a typical feature of shellfish allergy. Diagnosis, as for other food allergies, is based on SPTs and specific IgE, while the gold standard is DBPCFC. Cross-reactivity between shellfish is common and therefore, it is mandatory to avoid all shellfish. New immunotherapeutic strategies based on hypoallergens and other innovative approaches represent the new frontiers for desensitization.

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Section: Managementmentioning

confidence: 99%

IgE Mediated Shellfish Allergy in Children—A Review

et al. 2023

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“…However, common allergenic sources such as pollens and mites do indeed show cross-reactivity with food [ 119 , 120 ]. The effect of immunotherapy using pollen and house dust mite allergoids to treat associated food allergies is still little known [ 121 , 122 ], but it could be a promising way to treat food allergies in patients with allergen cross-reactivity. Overall, allergoids join the potential repertoire of chemical and physical processes targeting native proteins that are ultimately responsible for food allergy.…”

Section: Chemical/biochemical Deactivationmentioning

confidence: 99%

Food Allergens: When Friends Become Foes—Caveats and Opportunities for Oral Immunotherapy Based on Deactivation Methods

Gil,

Fernández-Rivera,

Pastor-Vargas

et al. 2023

Nutrients

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Food allergies represent a serious health concern and, since the 1990s, they have risen gradually in high-income countries. Unfortunately, the problem is complex because genetic, epigenetic, and environmental factors may be collectively involved. Prevention and diagnoses have not yet evolved into efficacious therapies. Identification and control of allergens present in edible substances hold promise for multi-purpose biomedical approaches, including oral immunotherapy. This review highlights recent studies and methods to modify the otherwise innocuous native proteins in most subjects, and how oral treatments targeting immune responses could help cancel out the potential risks in hypersensitive individuals, especially children. We have focused on some physical methods that can easily be conducted, along with chemo-enzymatic modifications of allergens by means of peptides and phytochemicals in particular. The latter, accessible from naturally-occurring substances, provide an added value to hypoallergenic matrices employing vegetal wastes, a point where food chemistry meets sustainable goals as well.

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House dust mite-specific immunotherapy and tropomyosin sensitizations: harm or benefit for patients?

Cited by 2 publications

References 0 publications

IgE Mediated Shellfish Allergy in Children—A Review

IgE Mediated Shellfish Allergy in Children—A Review

Food Allergens: When Friends Become Foes—Caveats and Opportunities for Oral Immunotherapy Based on Deactivation Methods

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