volume 79, issue 7, P1147-1154 2015
DOI: 10.1080/09168451.2015.1008975
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Junpei Yamamoto, Miki Tadaishi, Takumi Yamane, Yuichi Oishi, Makoto Shimizu, Kazuo Kobayashi-Hattori

Abstract: In this study, the antidiabetic effects of a hot water extract of edible Chrysanthemum morifolium Ramat. (HW-ECM) were investigated in type 2 diabetic mice. HW-ECM improved blood glucose levels and insulin resistance and increased adiponectin mRNA expression in adipose tissues and protein concentrations in the plasma. Moreover, it increased adipose mRNA and protein expressions of peroxisome proliferator-activated receptor γ (PPARγ), a regulator of adiponectin transcription, and mRNA expression of its downstrea…

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