Hot tub lung: an occupational hazard

Fjällbrant, Harald; Åkerström, Magnus; Svensson, Erik; Andersson, Eva

doi:10.1183/09059180.00002312

Cited by 33 publications

(16 citation statements)

References 10 publications

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“…Chemokines and cytokines also seem to play a role in macrophage activation, granuloma formation, and fibrosis. Individual susceptibility Khoor et al, 17 Morell et al, 28 Fjallbrant et al, 56 Mukhopadhyay, 57 Cormier, 58 Katzenstein and Askin, 79 Barrera et al, 80 Emanuel et al, 81 Nakajima et al, 82 Utsugi et al, 83 Yoo et al, 84 Orriols et al, 85 Jordan and Gey, 86 and Marcer et al 87 is poorly understood. Studies suggest a genetic link to the major histocompatibility complex because certain major histocompatibility complex haplotypes increase a person's susceptibility to developing HP.…”

Section: Pathogenesismentioning

confidence: 99%

Hypersensitivity Pneumonitis A Perspective From Members of the Pulmonary Pathology Society

Miller

Allen

Barrios

et al. 2018

Archives of Pathology & Laboratory Medicine

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- As a pathologist, it is important to consider hypersensitivity pneumonitis when examining lung specimens because it is often clinically and pathologically overlooked. Recognizing the often subtle findings and correlating them with the patient's history or suggesting a thorough clinical investigation of potential exposures can be of help in identifying the underlying condition so that the patient can be appropriately managed.

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Section: Pathogenesismentioning

confidence: 99%

Hypersensitivity Pneumonitis A Perspective From Members of the Pulmonary Pathology Society

Miller

Allen

Barrios

et al. 2018

Archives of Pathology & Laboratory Medicine

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“…Thus, it is likely that humans are exposed to NTM on a daily basis [10]. Simultaneously, behavioral changes such as the rising use of swimming pools and hot tub baths may increase the likelihood of exposure to NTM [14]. Third, ongoing advances in methodology in the mycobacteriology laboratory have led to enhanced isolation and more rapid and accurate identification of NTM from clinical specimens [1].…”

Section: Introductionmentioning

confidence: 99%

The Epidemiology of Pulmonary Nontuberculous Mycobacteria: Data from a General Hospital in Athens, Greece, 2007–2013

et al. 2014

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Background. The epidemiology of pulmonary nontuberculous mycobacteria (NTM) in Greece is largely unknown. Objectives. To determine the incidence and the demographic, microbiological, and clinical characteristics of patients with pulmonary NTM infection and pulmonary NTM disease. Methods. A retrospective review of the demographic, microbiological, and clinical characteristics of patients with NTM culture-positive respiratory specimens from January 2007 to May 2013. Results. A total of 120 patients were identified with at least one respiratory NTM isolate and 56 patients (46%) fulfilled the microbiological ATS/IDSA criteria for NTM disease. Of patients with adequate data, 16% fulfilled the complete ATS/IDSA criteria for NTM disease. The incidence of pulmonary NTM infection and disease was 18.9 and 8.8 per 100.000 inpatients and outpatients, respectively. The spectrum of NTM species was high (13 species) and predominated by M. avium-intracellulare complex (M. avium (13%), M. intracellulare (10%)), M. gordonae (14%), and M. fortuitum (12%). The ratio of isolation of NTM to M. tuberculosis in all hospitalized patients was 0.59. Conclusions. The first data on the epidemiology of pulmonary NTM in Athens, Greece, are presented. NTM infection is common in patients with chronic respiratory disease. However, only a significantly smaller proportion of patients fulfill the criteria for NTM disease.

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“…and a cross referencing of article references, returned 70 cases in the English literature. 1,2,8,[11][12][13][14][15][16] The articles mostly describe healthy middle aged individuals, with the mean age of 58.8 years (range 30 to 69). No sex predilection was noted (Males 51% and females 49%).…”

Section: Discussionmentioning

confidence: 99%